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Opposing roles for AMPK in regulating distinct mitophagy pathways.
Longo M, Bishnu A, Risiglione P, Montava-Garriga L, Cuenco J, Sakamoto K, MacKintosh C, Ganley IG. Longo M, et al. Among authors: ganley ig. Mol Cell. 2024 Nov 5:S1097-2765(24)00865-7. doi: 10.1016/j.molcel.2024.10.025. Online ahead of print. Mol Cell. 2024. PMID: 39532100 Free article.
PINK1 regulated mitophagy is evident in skeletal muscles.
Singh F, Wilhelm L, Prescott AR, Ostacolo K, Zhao JF, Ogmundsdottir MH, Ganley IG. Singh F, et al. Among authors: ganley ig. Autophagy Rep. 2024 Mar 11;3(1):2326402. doi: 10.1080/27694127.2024.2326402. Autophagy Rep. 2024. PMID: 38988500 Free PMC article.
Alterations of PINK1-PRKN signaling in mice during normal aging.
Baninameh Z, Watzlawik JO, Hou X, Richardson T, Kurchaba NW, Yan T, Di Florio DN, Fairweather D, Kang L, Nguyen JH, Kanekiyo T, Dickson DW, Noda S, Sato S, Hattori N, Goldberg MS, Ganley IG, Stauch KL, Fiesel FC, Springer W. Baninameh Z, et al. Among authors: ganley ig. bioRxiv [Preprint]. 2024 May 1:2024.04.29.591753. doi: 10.1101/2024.04.29.591753. bioRxiv. 2024. PMID: 38746191 Free PMC article. Preprint.
Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenosine confers neuroprotection regardless of glycaemic status.
Anderson A, Alfahad N, Wimalachandra D, Bouzinab K, Rudzinska P, Wood H, Fazey I, Xu H, Lyons TJ, Barnes NM, Narendran P, Lord JM, Rauz S, Ganley IG, Curtis TM, Wallace GR, Hombrebueno JR. Anderson A, et al. Among authors: ganley ig. Nat Commun. 2024 Feb 6;15(1):1124. doi: 10.1038/s41467-024-45387-9. Nat Commun. 2024. PMID: 38321058 Free PMC article.
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.
Fang TZ, Sun Y, Pearce AC, Eleuteri S, Kemp M, Luckhurst CA, Williams R, Mills R, Almond S, Burzynski L, Márkus NM, Lelliott CJ, Karp NA, Adams DJ, Jackson SP, Zhao JF, Ganley IG, Thompson PW, Balmus G, Simon DK. Fang TZ, et al. Among authors: ganley ig. Nat Commun. 2023 Nov 13;14(1):7295. doi: 10.1038/s41467-023-42876-1. Nat Commun. 2023. PMID: 37957154 Free PMC article.
Nrf2 depletion in the context of loss-of-function Keap1 leads to mitolysosome accumulation.
Dayalan Naidu S, Angelova PR, Knatko EV, Leonardi C, Novak M, de la Vega L, Ganley IG, Abramov AY, Dinkova-Kostova AT. Dayalan Naidu S, et al. Among authors: ganley ig. Free Radic Biol Med. 2023 Nov 1;208:478-493. doi: 10.1016/j.freeradbiomed.2023.09.009. Epub 2023 Sep 14. Free Radic Biol Med. 2023. PMID: 37714439 Free article.
AUTOPHAGY IN THE EYE: FROM PHYSIOLOGY TO PATHOPHYSOLOGY.
Liton PB, Boesze-Battaglia K, Boulton ME, Boya P, Ferguson TA, Ganley IG, Kauppinnen A, Laurie GW, Mizushima N, Morishita H, Russo R, Sadda J, Shyam R, Sinha D, Thompson DA, Zacks DN. Liton PB, et al. Among authors: ganley ig. Autophagy Rep. 2023;2(1):2178996. doi: 10.1080/27694127.2023.2178996. Epub 2023 Mar 1. Autophagy Rep. 2023. PMID: 37034386 Free PMC article.
76 results