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Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical probability.
Therriault J, Janelidze S, Benedet AL, Ashton NJ, Arranz Martínez J, Gonzalez-Escalante A, Bellaver B, Alcolea D, Vrillon A, Karim H, Mielke MM, Hyung Hong C, Roh HW, Contador J, Puig Pijoan A, Algeciras-Schimnich A, Vemuri P, Graff-Radford J, Lowe VJ, Karikari TK, Jonaitis E, Brum W, Tissot C, Servaes S, Rahmouni N, Macedo AC, Stevenson J, Fernandez-Arias J, Wang YT, Woo MS, Friese MA, Jia WL, Dumurgier J, Hourregue C, Cognat E, Ferreira PL, Vitali P, Johnson S, Pascoal TA, Gauthier S, Lleó A, Paquet C, Petersen RC, Salmon D, Mattsson-Carlgren N, Palmqvist S, Stomrud E, Galasko D, Son SJ, Zetterberg H, Fortea J, Suárez-Calvet M, Jack CR Jr, Blennow K, Hansson O, Rosa-Neto P. Therriault J, et al. Among authors: pascoal ta. Nat Aging. 2024 Nov;4(11):1529-1537. doi: 10.1038/s43587-024-00731-y. Epub 2024 Nov 12. Nat Aging. 2024. PMID: 39533113 Free PMC article.
Identification of late-stage tau accumulation using plasma phospho-tau217.
Woo MS, Therriault J, Jonaitis EM, Wilson R, Langhough RE, Rahmouni N, Benedet AL, Ashton NJ, Tissot C, Lantero-Rodriguez J, Macedo AC, Servaes S, Wang YT, Arias JF, Hosseini SA, Betthauser TJ, Lussier FZ, Hopewell R, Triana-Baltzer G, Kolb HC, Jeromin A, Kobayashi E, Massarweh G, Friese MA, Klostranec J, Vilali P, Pascoal TA, Gauthier S, Zetterberg H, Blennow K, Johnson SC, Rosa-Neto P. Woo MS, et al. Among authors: pascoal ta. EBioMedicine. 2024 Nov;109:105413. doi: 10.1016/j.ebiom.2024.105413. Epub 2024 Nov 4. EBioMedicine. 2024. PMID: 39500009 Free PMC article.
Comparison Between Brain and Cerebellar Autoradiography Using [18F]Flortaucipir, [18F]MK6240, and [18F]PI2620 in Postmortem Human Brain Tissue.
Aliaga A, Therriault J, Quispialaya KM, Aliaga A, Hopewell R, Rahmouni N, Macedo AC, Kunach P, Soucy JP, Massarweh G, Diaz AA, Pascoal TA, Rocha A, Guiot MC, Machado LS, De Bastiani MA, de Souza DG, Souza DO, Gauthier S, Zimmer ER, Rosa-Neto P. Aliaga A, et al. Among authors: pascoal ta. J Nucl Med. 2024 Oct 30:jnumed.124.267539. doi: 10.2967/jnumed.124.267539. Online ahead of print. J Nucl Med. 2024. PMID: 39477493
Plasma phosphorylated tau181 outperforms [18F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer disease.
Quispialaya KM, Therriault J, Aliaga A, Tissot C, Servaes S, Rahmouni N, Karikari TK, Benedet AL, Ashton NJ, Macedo AC, Lussier FZ, Stevenson J, Wang YT, Arias JF, Hosseini A, Matsudaira T, Jean-Claude B, Gilfix BM, Zimmer ER, Soucy JP, Pascoal TA, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Quispialaya KM, et al. Among authors: pascoal ta. Eur J Neurol. 2024 Dec;31(12):e16255. doi: 10.1111/ene.16255. Epub 2024 Oct 24. Eur J Neurol. 2024. PMID: 39447157 Free PMC article.
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease.
Zeng X, Lafferty TK, Sehrawat A, Chen Y, Ferreira PCL, Bellaver B, Povala G, Kamboh MI, Klunk WE, Cohen AD, Lopez OL, Ikonomovic MD, Pascoal TA, Ganguli M, Villemagne VL, Snitz BE, Karikari TK. Zeng X, et al. Among authors: pascoal ta. Mol Neurodegener. 2024 Oct 10;19(1):68. doi: 10.1186/s13024-024-00753-5. Mol Neurodegener. 2024. PMID: 39385222 Free PMC article.
Insights into the use of biomarkers in clinical trials in Alzheimer's disease.
Pascoal TA, Aguzzoli CS, Lussier FZ, Crivelli L, Suemoto CK, Fortea J, Rosa-Neto P, Zimmer ER, Ferreira PCL, Bellaver B. Pascoal TA, et al. EBioMedicine. 2024 Oct;108:105322. doi: 10.1016/j.ebiom.2024.105322. Epub 2024 Oct 3. EBioMedicine. 2024. PMID: 39366844 Free PMC article. Review.
Modeling the progression of neuropsychiatric symptoms in Alzheimer's disease with PET-based Braak staging.
Macedo AC, Therriault J, Tissot C, Aumont É, Servaes S, Rahmouni N, Fernandez-Arias J, Lussier FZ, Wang YT, Ng KP, Vermeiren M, Bezgin G, Socualaya KQ, Stevenson J, Hosseini SA, Chamoun M, Ferrari-Souza JP, Ferreira PCL, Bellaver B, Leffa DT, Vitali P, Zimmer ER, Ismail Z, Pascoal TA, Gauthier S, Rosa-Neto P. Macedo AC, et al. Among authors: pascoal ta. Neurobiol Aging. 2024 Dec;144:127-137. doi: 10.1016/j.neurobiolaging.2024.09.009. Epub 2024 Sep 20. Neurobiol Aging. 2024. PMID: 39326302 Free article.
Influence of Different Diagnostic Criteria on Alzheimer Disease Clinical Research.
Bieger A, Brum WS, Borelli WV, Therriault J, De Bastiani MA, Moreira AG, Benedet AL, Ferrari-Souza JP, Da Costa JC, Souza DO, Castilhos RM, Schumacher Schuh AF, Fagundes Chaves ML, Schöll M, Zetterberg H, Blennow K, Pascoal TA, Gauthier S, Rosa-Neto P, Schilling LP, Zimmer ER; Alzheimer's Disease Neuroimaging Initiative. Bieger A, et al. Among authors: pascoal ta. Neurology. 2024 Sep 10;103(5):e209753. doi: 10.1212/WNL.0000000000209753. Epub 2024 Aug 21. Neurology. 2024. PMID: 39167736
Omics-derived biological modules reflect metabolic brain changes in Alzheimer's disease.
Povala G, De Bastiani MA, Bellaver B, Ferreira PCL, Ferrari-Souza JP, Lussier FZ, Souza DO, Rosa-Neto P, Pascoal TA, Zatt B, Zimmer ER; Alzheimer's Disease Neuroimaging Initiative. Povala G, et al. Among authors: pascoal ta. Alzheimers Dement. 2024 Oct;20(10):6709-6721. doi: 10.1002/alz.14095. Epub 2024 Aug 14. Alzheimers Dement. 2024. PMID: 39140361 Free PMC article.
149 results