Cook AL - Search Results

1

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease.

Han J, Chear S, Talbot J, Swier V, Booth C, Reuben-Thomas C, Dalvi S, Weimer JM, Hewitt AW, Cook AL, Singh R. Han J, et al. Among authors: cook al. Invest Ophthalmol Vis Sci. 2024 Nov 4;65(13):23. doi: 10.1167/iovs.65.13.23. Invest Ophthalmol Vis Sci. 2024. PMID: 39535788 Free PMC article.

2

Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons.

Chear S, Perry S, Wilson R, Bindoff A, Talbot J, Ware TL, Grubman A, Vickers JC, Pébay A, Ruddle JB, King AE, Hewitt AW, Cook AL. Chear S, et al. Among authors: cook al. Dis Model Mech. 2022 Dec 1;15(12):dmm049651. doi: 10.1242/dmm.049651. Epub 2022 Dec 13. Dis Model Mech. 2022. PMID: 36453132 Free PMC article.

3

Use of CRISPR/Cas ribonucleoproteins for high throughput gene editing of induced pluripotent stem cells.

Wang Q, Chear S, Wing K, Stellon D, Nguyen Tran MT, Talbot J, Pébay A, Hewitt AW, Cook AL. Wang Q, et al. Among authors: cook al. Methods. 2021 Oct;194:18-29. doi: 10.1016/j.ymeth.2021.02.009. Epub 2021 Feb 17. Methods. 2021. PMID: 33607266

4

Image-Based Quantitation of Kainic Acid-Induced Excitotoxicity as a Model of Neurodegeneration in Human iPSC-Derived Neurons.

Talbot J, Chear S, Phipps A, Pébay A, Hewitt AW, Vickers JC, King AE, Cook AL. Talbot J, et al. Among authors: cook al. Methods Mol Biol. 2022;2549:187-207. doi: 10.1007/7651_2021_421. Methods Mol Biol. 2022. PMID: 34505266

5

CRISPR/Cas-Mediated Knock-in of Genetically Encoded Fluorescent Biosensors into the AAVS1 Locus of Human-Induced Pluripotent Stem Cells.

Stellon D, Tran MTN, Talbot J, Chear S, Khalid MKNM, Pébay A, Vickers JC, King AE, Hewitt AW, Cook AL. Stellon D, et al. Among authors: cook al. Methods Mol Biol. 2022;2549:379-398. doi: 10.1007/7651_2021_422. Methods Mol Biol. 2022. PMID: 34505269

6

Seeing Neurodegeneration in a New Light Using Genetically Encoded Fluorescent Biosensors and iPSCs.

Stellon D, Talbot J, Hewitt AW, King AE, Cook AL. Stellon D, et al. Among authors: cook al. Int J Mol Sci. 2023 Jan 16;24(2):1766. doi: 10.3390/ijms24021766. Int J Mol Sci. 2023. PMID: 36675282 Free PMC article. Review.

7

Genetic and cellular basis of impaired phagocytosis and photoreceptor degeneration in CLN3 disease.

Han J, Chear S, Talbot J, Swier V, Booth C, Reuben-Thomas C, Dalvi S, Weimer JM, Hewitt AW, Cook AL, Singh R. Han J, et al. Among authors: cook al. bioRxiv [Preprint]. 2024 Jun 13:2024.06.09.597388. doi: 10.1101/2024.06.09.597388. bioRxiv. 2024. Update in: Invest Ophthalmol Vis Sci. 2024 Nov 4;65(13):23. doi: 10.1167/iovs.65.13.23 PMID: 38895469 Free PMC article. Updated. Preprint.

8

Peeking into the molecular trove of discarded surgical specimens.

Hewitt AW, Cook AL, Pébay A. Hewitt AW, et al. Among authors: cook al. Clin Exp Ophthalmol. 2016 Nov;44(8):661-662. doi: 10.1111/ceo.12837. Clin Exp Ophthalmol. 2016. PMID: 27870490 No abstract available.

9

Culture Variabilities of Human iPSC-Derived Cerebral Organoids Are a Major Issue for the Modelling of Phenotypes Observed in Alzheimer's Disease.

Hernández D, Rooney LA, Daniszewski M, Gulluyan L, Liang HH, Cook AL, Hewitt AW, Pébay A. Hernández D, et al. Among authors: cook al. Stem Cell Rev Rep. 2022 Feb;18(2):718-731. doi: 10.1007/s12015-021-10147-5. Epub 2021 Mar 16. Stem Cell Rev Rep. 2022. PMID: 33725267

10

Induced pluripotent stem cell derived pericytes respond to mediators of proliferation and contractility.

King NE, Courtney JM, Brown LS, Fortune AJ, Blackburn NB, Fletcher JL, Cashion JM, Talbot J, Pébay A, Hewitt AW, Morris GP, Young KM, Cook AL, Sutherland BA. King NE, et al. Among authors: cook al. Stem Cell Res Ther. 2024 Mar 3;15(1):59. doi: 10.1186/s13287-024-03671-x. Stem Cell Res Ther. 2024. PMID: 38433209 Free PMC article.

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