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Adipocyte lipin 1 expression associates with human metabolic health and regulates systemic metabolism in mice.
LaPoint A, Singer JM, Ferguson D, Shew TM, Renkemeyer MK, Palacios HH, Field RL, Yerrathota S, Kumari R, Shankaran M, Smith GI, Yoshino J, He M, Patti GJ, Hellerstein MK, Klein S, Morris EM, Brestoff JR, Finck BN, Lutkewitte A. LaPoint A, et al. Among authors: ferguson d. J Clin Invest. 2024 Oct 15:e169722. doi: 10.1172/JCI169722. Online ahead of print. J Clin Invest. 2024. PMID: 39405118 Free article.
Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with In Vivo Target Engagement.
Frey RR, Jana N, Gorman JV, Wang J, Smith HA, Bromberg KD, Thakur A, Doktor SZ, Indulkar AS, Jakob CG, Upadhyay AK, Qiu W, Manaves V, Gambino F Jr, Valentino SA, Montgomery D, Zhou Y, Li T, Buchanan FG, Ferguson DC, Kurnick MD, Kapecki N, Lai A, Michaelides MR, Penning TD. Frey RR, et al. Among authors: ferguson dc. J Med Chem. 2024 Oct 10;67(19):17033-17052. doi: 10.1021/acs.jmedchem.4c01451. Epub 2024 Sep 30. J Med Chem. 2024. PMID: 39350472
Genome-wide association study between SARS-CoV-2 single nucleotide polymorphisms and virus copies during infections.
Li K, Chaguza C, Stamp J, Chew YT, Chen NFG, Ferguson D, Pandya S, Kerantzas N, Schulz W; Yale SARS-CoV-2 Genomic Surveillance Initiative; Hahn AM, Ogbunugafor CB, Pitzer VE, Crawford L, Weinberger DM, Grubaugh ND. Li K, et al. Among authors: ferguson d. PLoS Comput Biol. 2024 Sep 17;20(9):e1012469. doi: 10.1371/journal.pcbi.1012469. eCollection 2024 Sep. PLoS Comput Biol. 2024. PMID: 39288189 Free PMC article.
Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor.
Yu Y, Jang M, Miyashiro J, Clark RF, Zhu GD, Gong J, Dai Y, Frey RR, Penning TD, Kim H, Lee HK, Kim JK, Ryu KM, Park SJ, Yoon T, Li T, Kurnick MD, Kapecki NJ, Li L, Gorman JV, Montgomery DA, Manaves V, Bromberg KD, Doktor SZ, Thakur A, Wang J, Smith HA, Buchanan FG, Ferguson DC, Torrent M, Jakob CG, Qiu W, Upadhyay AK, Martin RL, Lai A, Michaelides MR. Yu Y, et al. Among authors: ferguson dc. J Med Chem. 2024 Oct 10;67(19):17000-17032. doi: 10.1021/acs.jmedchem.4c01450. Epub 2024 Sep 16. J Med Chem. 2024. PMID: 39283694
Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation.
Zeeshan M, Rashpa R, Ferguson DJ, Mckeown G, Nugmanova R, Subudhi AK, Beyeler R, Pashley SL, Markus R, Brady D, Roques M, Bottrill AR, Fry AM, Pain A, Vaughan S, Holder AA, Tromer EC, Brochet M, Tewari R. Zeeshan M, et al. Among authors: ferguson dj. PLoS Biol. 2024 Sep 10;22(9):e3002802. doi: 10.1371/journal.pbio.3002802. eCollection 2024 Sep. PLoS Biol. 2024. PMID: 39255311 Free PMC article.
2,139 results