Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease.
Kerrigan JR, Thomsen NM, Cernijenko A, Kochanek SE, Dewhurst J, O'Brien G, Ware NF, Sanchez CC, Manning JR, Ma X, Ornelas E, Savage NA, Partridge JR, Patterson AW, Lam P, Dales NA, Bonazzi S, Borikar S, Hinman AE, Ting PY.
Kerrigan JR, et al. Among authors: ma x.
J Med Chem. 2024 Nov 14. doi: 10.1021/acs.jmedchem.4c02251. Online ahead of print.
J Med Chem. 2024.
PMID: 39541509