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The First-In-Class Deubiquitinase-Targeting Chimera Stabilizes and Activates cGAS.
Deng Z, Chen L, Qian C, Liu J, Wu Q, Song X, Xiong Y, Wang Z, Hu X, Inuzuka H, Zhong Y, Xiang Y, Lin Y, Dung Pham N, Shi Y, Wei W, Jin J. Deng Z, et al. Among authors: inuzuka h. Angew Chem Int Ed Engl. 2024 Aug 16:e202415168. doi: 10.1002/anie.202415168. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39150898
HHIP protein interactions in lung cells provide insight into COPD pathogenesis.
Deritei D, Inuzuka H, Castaldi PJ, Yun JH, Xu Z, Anamika WJ, Asara JM, Guo F, Zhou X, Glass K, Wei W, Silverman EK. Deritei D, et al. Among authors: inuzuka h. bioRxiv [Preprint]. 2024 Apr 1:2024.04.01.586839. doi: 10.1101/2024.04.01.586839. bioRxiv. 2024. PMID: 38617310 Free PMC article. Preprint.
USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK.
Liu J, Hu X, Luo K, Xiong Y, Chen L, Wang Z, Inuzuka H, Qian C, Yu X, Xie L, Muneer A, Zhang D, Paulo JA, Chen X, Jin J, Wei W. Liu J, et al. Among authors: inuzuka h. J Am Chem Soc. 2024 Apr 10. doi: 10.1021/jacs.4c02373. Online ahead of print. J Am Chem Soc. 2024. PMID: 38597345
Identification of a distal enhancer regulating hedgehog interacting protein gene in human lung epithelial cells.
Guo F, Zhang L, Yu Y, Gong L, Tao S, Werder RB, Mishra S, Zhou Y, Anamika WJ, Lao T, Inuzuka H, Zhang Y, Pham B, Liu T, Tufenkjian TS, Richmond BW, Wei W, Mou H, Wilson AA, Hu M, Chen W, Zhou X. Guo F, et al. Among authors: inuzuka h. EBioMedicine. 2024 Mar;101:105026. doi: 10.1016/j.ebiom.2024.105026. Epub 2024 Feb 27. EBioMedicine. 2024. PMID: 38417378 Free PMC article.
USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice.
Dang F, Bai L, Dong J, Hu X, Wang J, Paulo JA, Xiong Y, Liang X, Sun Y, Chen Y, Guo M, Wang X, Huang Z, Inuzuka H, Chen L, Chu C, Liu J, Zhang T, Rezaeian AH, Liu J, Kaniskan HÜ, Zhong B, Zhang J, Letko M, Jin J, Lan K, Wei W. Dang F, et al. Among authors: inuzuka h. Sci Transl Med. 2023 Dec 6;15(725):eadh7668. doi: 10.1126/scitranslmed.adh7668. Epub 2023 Dec 6. Sci Transl Med. 2023. PMID: 38055802
159 results