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Page 1
Proteomic and functional comparison between human induced and embryonic stem cells.
Brenes AJ, Griesser E, Sinclair LV, Davidson L, Prescott AR, Singh F, Hogg EKJ, Espejo-Serrano C, Jiang H, Yoshikawa H, Platani M, Swedlow JR, Findlay GM, Cantrell DA, Lamond AI. Brenes AJ, et al. Among authors: sinclair lv. Elife. 2024 Nov 14;13:RP92025. doi: 10.7554/eLife.92025. Elife. 2024. PMID: 39540879 Free PMC article.
Deep proteomic analysis of microglia reveals fundamental biological differences between model systems.
Lloyd AF, Martinez-Muriana A, Davis E, Daniels MJD, Hou P, Mancuso R, Brenes AJ, Sinclair LV, Geric I, Snellinx A, Craessaerts K, Theys T, Fiers M, De Strooper B, Howden AJM. Lloyd AF, et al. Among authors: sinclair lv. Cell Rep. 2024 Oct 25;43(11):114908. doi: 10.1016/j.celrep.2024.114908. Online ahead of print. Cell Rep. 2024. PMID: 39460937 Free article.
Airway macrophage glycolysis controls lung homeostasis and responses to aeroallergen.
Albers GJ, Michalaki C, Ogger PP, Lloyd AF, Causton B, Walker SA, Caldwell A, Halket JM, Sinclair LV, Forde SH, McCarthy C, Hinks TSC, Lloyd CM, Byrne AJ. Albers GJ, et al. Among authors: sinclair lv. Mucosal Immunol. 2024 Oct 18:S1933-0219(24)00105-3. doi: 10.1016/j.mucimm.2024.10.002. Online ahead of print. Mucosal Immunol. 2024. PMID: 39426627 Free article.
Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions.
Ryan EK, Clutter C, De Barra C, Jenkins BJ, O'Shaughnessy S, Ryan OK, McKenna C, Heneghan HM, Walsh F, Finlay DK, Sinclair LV, Jones N, Leung DT, O'Shea D, Hogan AE. Ryan EK, et al. Among authors: sinclair lv. J Immunol. 2024 Jun 1;212(11):1706-1713. doi: 10.4049/jimmunol.2300649. J Immunol. 2024. PMID: 38619286 Free PMC article.
Glycogen-fuelled metabolism supports rapid mucosal-associated invariant T cell responses.
Cassidy FC, Kedia-Mehta N, Bergin R, Woodcock A, Berisha A, Bradley B, Booth E, Jenkins BJ, Ryan OK, Jones N, Sinclair LV, O'Shea D, Hogan AE. Cassidy FC, et al. Among authors: sinclair lv. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2300566120. doi: 10.1073/pnas.2300566120. Epub 2023 Jun 12. Proc Natl Acad Sci U S A. 2023. PMID: 37307453 Free PMC article.
Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.
Jenkins BJ, Blagih J, Ponce-Garcia FM, Canavan M, Gudgeon N, Eastham S, Hill D, Hanlon MM, Ma EH, Bishop EL, Rees A, Cronin JG, Jury EC, Dimeloe SK, Veale DJ, Thornton CA, Vousden KH, Finlay DK, Fearon U, Jones GW, Sinclair LV, Vincent EE, Jones N. Jenkins BJ, et al. Among authors: sinclair lv. Cell Metab. 2023 Jul 11;35(7):1132-1146.e9. doi: 10.1016/j.cmet.2023.05.001. Epub 2023 May 24. Cell Metab. 2023. PMID: 37230079 Free article.
The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis.
Kedia-Mehta N, Pisarska MM, Rollings C, O'Neill C, De Barra C, Foley C, Wood NAW, Wrigley-Kelly N, Veerapen N, Besra G, Bergin R, Jones N, O'Shea D, Sinclair LV, Hogan AE. Kedia-Mehta N, et al. Among authors: sinclair lv. Sci Signal. 2023 Apr 18;16(781):eabo2709. doi: 10.1126/scisignal.abo2709. Epub 2023 Apr 18. Sci Signal. 2023. PMID: 37071733
35 results