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Discovery of 1-(Phenylsulfonyl)-1,2,3,4-tetrahydroquinoline Derivative as Orally Bioavailable and Safe RORγt Inverse Agonists for Potential Treatment of Rheumatoid Arthritis.
Sun SL, Xu HJ, Jiang XL, Zhou J, Shi W, Wang XJ, Song W, Chang XY, Ma XQ, Zou XF, Wu SH, Yang J, Li QQ, Wang ZX, Cai J, Yu SP, Wang QX, Wei TH, Wu JZ, Tong ZJ, Zhou Y, Wang YB, Yu YC, Leng XJ, Ding N, Shi ZH, Dai WC, Xue X, Li NG, Wang XL. Sun SL, et al. Among authors: wang xj, wang xl. J Med Chem. 2024 Nov 15. doi: 10.1021/acs.jmedchem.4c01727. Online ahead of print. J Med Chem. 2024. PMID: 39546350
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