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PTEN deletion in the adult dentate gyrus induces epilepsy.
Yonan JM, Chen KD, Baram TZ, Steward O. Yonan JM, et al. Among authors: steward o. Neurobiol Dis. 2024 Nov 13:106736. doi: 10.1016/j.nbd.2024.106736. Online ahead of print. Neurobiol Dis. 2024. PMID: 39547478
Spontaneously regenerative corticospinal neurons in mice.
Fait BW, Cotto B, Murakami TC, Hagemann-Jensen M, Zhan H, Freivald C, Turbek I, Gao Y, Yao Z, Way SW, Zeng H, Tasic B, Steward O, Heintz N, Schmidt EF. Fait BW, et al. Among authors: steward o. bioRxiv [Preprint]. 2024 Sep 12:2024.09.09.612115. doi: 10.1101/2024.09.09.612115. bioRxiv. 2024. PMID: 39314356 Free PMC article. Preprint.
PTEN DELETION IN THE ADULT DENTATE GYRUS INDUCES EPILEPSY.
Yonan JM, Chen KD, Baram TZ, Steward O. Yonan JM, et al. Among authors: steward o. bioRxiv [Preprint]. 2024 Aug 9:2024.08.07.606938. doi: 10.1101/2024.08.07.606938. bioRxiv. 2024. PMID: 39149280 Free PMC article. Preprint.
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.
Smith JM, Barlaam B, Beattie D, Bradshaw L, Chan HM, Chiarparin E, Collingwood O, Cooke SL, Cronin A, Cumming I, Dean E, Debreczeni JÉ, Del Barco Barrantes I, Diene C, Gianni D, Guerot C, Guo X, Guven S, Hayhow TG, Hong T, Kemmitt PD, Lamont GM, Lamont S, Lynch JT, McWilliams L, Moore S, Raubo P, Robb GR, Robinson J, Scott JS, Srinivasan B, Steward O, Stubbs CJ, Syson K, Tan L, Turner O, Underwood E, Urosevic J, Vazquez-Chantada M, Whittaker AL, Wilson DM, Winter-Holt JJ. Smith JM, et al. Among authors: steward o. J Med Chem. 2024 Aug 22;67(16):13604-13638. doi: 10.1021/acs.jmedchem.4c00097. Epub 2024 Jul 30. J Med Chem. 2024. PMID: 39080842
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390.
Pike KG, Hunt TA, Barlaam B, Benstead D, Cadogan E, Chen K, Cook CR, Colclough N, Deng C, Durant ST, Eatherton A, Goldberg K, Johnström P, Liu L, Liu Z, Nissink JWM, Pang C, Pass M, Robb GR, Roberts C, Schou M, Steward O, Sykes A, Yan Y, Zhai B, Zheng L. Pike KG, et al. Among authors: steward o. J Med Chem. 2024 Feb 22;67(4):3090-3111. doi: 10.1021/acs.jmedchem.3c02277. Epub 2024 Feb 2. J Med Chem. 2024. PMID: 38306388
Human Motor Endplate Survival after Chronic Peripheral Nerve Injury.
Gupta R, Johnston TR, Chen VY, Gonzales LP, Steward O. Gupta R, et al. Among authors: steward o. medRxiv [Preprint]. 2023 Oct 14:2023.10.12.23296760. doi: 10.1101/2023.10.12.23296760. medRxiv. 2023. PMID: 37873401 Free PMC article. Preprint.
327 results