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Load-dependence of the activation of myosin filaments in heart muscle.
Wang Y, Fusi L, Ovejero JG, Hill C, Juma S, Cullup FP, Ghisleni A, Park-Holohan SJ, Ma W, Irving T, Narayanan T, Irving M, Brunello E. Wang Y, et al. Among authors: irving t. J Physiol. 2024 Nov 17. doi: 10.1113/JP287434. Online ahead of print. J Physiol. 2024. PMID: 39552044
Calcium has a direct effect on thick filament activation in porcine myocardium.
Mohran S, McMillen TS, Mandrycky C, Tu AY, Kooiker KB, Qian W, Neys S, Osegueda B, Moussavi-Harami F, Irving TC, Regnier M, Ma W. Mohran S, et al. Among authors: irving tc. J Gen Physiol. 2024 Nov 4;156(11):e202413545. doi: 10.1085/jgp.202413545. Epub 2024 Sep 20. J Gen Physiol. 2024. PMID: 39302315
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients.
van den Berg M, Shi Z, Claassen WJ, Hooijman P, Lewis CTA, Andersen JL, van der Pijl RJ, Bogaards SJP, Conijn S, Peters EL, Begthel LPL, Uijterwijk B, Lindqvist J, Langlais PR, Girbes ARJ, Stapel S, Granzier H, Campbell KS, Ma W, Irving T, Hwee DT, Hartman JJ, Malik FI, Paul M, Beishuizen A, Ochala J, Heunks L, Ottenheijm CAC. van den Berg M, et al. Among authors: irving t. Sci Transl Med. 2024 Jul 31;16(758):eadg3894. doi: 10.1126/scitranslmed.adg3894. Epub 2024 Jul 31. Sci Transl Med. 2024. PMID: 39083588
Mechanisms of a novel regulatory light chain-dependent cardiac myosin inhibitor.
Kooiker K, Gan QF, Yu M, Sa N, Mohran S, Cheng Y, Flint G, Neys S, Gao C, Nissen D, McMillen T, Asencio A, Ma W, Irving TC, Moussavi-Harami F, Regnier M. Kooiker K, et al. Among authors: irving tc. J Gen Physiol. 2024 Oct 7;156(10):e202313503. doi: 10.1085/jgp.202313503. Epub 2024 Jul 31. J Gen Physiol. 2024. PMID: 39083045
MuscleX: data analysis software for fiber diffraction patterns from muscle.
Jiratrakanvong J, Shao J, Li J, Menendez Alvarez M, Li X, Das P, Nikseresht G, Miskin N, Huo R, Nabon J, Leduc T, Zhang E, Ma W, Agam G, Irving TC. Jiratrakanvong J, et al. Among authors: irving tc. J Synchrotron Radiat. 2024 Sep 1;31(Pt 5):1401-1408. doi: 10.1107/S1600577524006167. Epub 2024 Jul 30. J Synchrotron Radiat. 2024. PMID: 39078694 Free PMC article.
224 results