Fraser HB - Search Results

1

Massively parallel experimental interrogation of natural variants in ancient signaling pathways reveals both purifying selection and local adaptation.

Aguilar-Rodríguez J, Vila J, Chen SA, Razo-Mejia M, Ghosh O, Fraser HB, Jarosz DF, Petrov DA. Aguilar-Rodríguez J, et al. Among authors: fraser hb. bioRxiv [Preprint]. 2024 Oct 31:2024.10.30.621178. doi: 10.1101/2024.10.30.621178. bioRxiv. 2024. PMID: 39553990 Free PMC article. Preprint.

2

A general principle governing neuronal evolution reveals a human-accelerated neuron type potentially underlying the high prevalence of autism in humans.

Starr AL, Fraser HB. Starr AL, et al. Among authors: fraser hb. bioRxiv [Preprint]. 2024 Aug 3:2024.08.02.606407. doi: 10.1101/2024.08.02.606407. bioRxiv. 2024. PMID: 39131279 Free PMC article. Preprint.

3

Disentangling cell-intrinsic and extrinsic factors underlying evolution.

Starr AL, Nishimura T, Igarashi KJ, Funamoto C, Nakauchi H, Fraser HB. Starr AL, et al. Among authors: fraser hb. bioRxiv [Preprint]. 2024 Aug 4:2024.05.06.592777. doi: 10.1101/2024.05.06.592777. bioRxiv. 2024. PMID: 38798687 Free PMC article. Preprint.

4

Cell-type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells.

Wang B, Starr AL, Fraser HB. Wang B, et al. Among authors: fraser hb. Elife. 2024 Feb 15;12:RP89594. doi: 10.7554/eLife.89594. Elife. 2024. PMID: 38358392 Free PMC article.

5

Chromatin activity identifies differential gene regulation across human ancestries.

Pettie KP, Mumbach M, Lea AJ, Ayroles J, Chang HY, Kasowski M, Fraser HB. Pettie KP, et al. Among authors: fraser hb. Genome Biol. 2024 Jan 15;25(1):21. doi: 10.1186/s13059-024-03165-2. Genome Biol. 2024. PMID: 38225662 Free PMC article.

6

Allele-specific expression reveals genetic drivers of tissue regeneration in mice.

Mack KL, Talbott HE, Griffin MF, Parker JBL, Guardino NJ, Spielman AF, Davitt MF, Mascharak S, Downer M, Morgan A, Valencia C, Akras D, Berger MJ, Wan DC, Fraser HB, Longaker MT. Mack KL, et al. Among authors: fraser hb. Cell Stem Cell. 2023 Oct 5;30(10):1368-1381.e6. doi: 10.1016/j.stem.2023.08.010. Epub 2023 Sep 14. Cell Stem Cell. 2023. PMID: 37714154 Free PMC article.

7

Cell type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells.

Wang B, Starr AL, Fraser HB. Wang B, et al. Among authors: fraser hb. bioRxiv [Preprint]. 2023 Sep 25:2023.05.22.541747. doi: 10.1101/2023.05.22.541747. bioRxiv. 2023. Update in: Elife. 2024 Feb 15;12:RP89594. doi: 10.7554/eLife.89594 PMID: 37292820 Free PMC article. Updated. Preprint.

8

Gene-by-environment interactions are pervasive among natural genetic variants.

Chen SA, Kern AF, Ang RML, Xie Y, Fraser HB. Chen SA, et al. Among authors: fraser hb. Cell Genom. 2023 Feb 28;3(4):100273. doi: 10.1016/j.xgen.2023.100273. eCollection 2023 Apr 12. Cell Genom. 2023. PMID: 37082145 Free PMC article.

9

Widespread epistasis among beneficial genetic variants revealed by high-throughput genome editing.

Ang RML, Chen SA, Kern AF, Xie Y, Fraser HB. Ang RML, et al. Among authors: fraser hb. Cell Genom. 2023 Feb 28;3(4):100260. doi: 10.1016/j.xgen.2023.100260. eCollection 2023 Apr 12. Cell Genom. 2023. PMID: 37082144 Free PMC article.

10

Evolution of Spatial and Temporal cis-Regulatory Divergence in Sticklebacks.

Mack KL, Square TA, Zhao B, Miller CT, Fraser HB. Mack KL, et al. Among authors: fraser hb. Mol Biol Evol. 2023 Mar 4;40(3):msad034. doi: 10.1093/molbev/msad034. Mol Biol Evol. 2023. PMID: 36805962 Free PMC article.

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