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Spatial Expression of Long Non-Coding RNAs in Human Brains of Alzheimer's Disease.
Ng B, Avey DR, Lopes KP, Fujita M, Vialle RA, Vyas H, Kearns NA, Tasaki S, Iatrou A, Tissera S, Chang TH, Xu J, Yu C, Sultan F, Menon V, Gaiteri C, De Jager PL, Bennett DA, Wang Y. Ng B, et al. Among authors: de jager pl. bioRxiv [Preprint]. 2025 Jan 4:2024.10.27.620550. doi: 10.1101/2024.10.27.620550. bioRxiv. 2025. PMID: 39554066 Free PMC article. Preprint.
Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.
Oveisgharan S, Yang J, Yu L, Burba D, Bang W, Tasaki S, Grodstein F, Wang Y, Zhao J, De Jager PL, Schneider JA, Bennett DA. Oveisgharan S, et al. Among authors: de jager pl. Neurology. 2023 Apr 4;100(14):e1474-e1487. doi: 10.1212/WNL.0000000000206833. Epub 2023 Jan 25. Neurology. 2023. PMID: 36697247 Free PMC article.
Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts.
Zhou W, Karan KR, Gu W, Klein HU, Sturm G, De Jager PL, Bennett DA, Hirano M, Picard M, Mills RE. Zhou W, et al. Among authors: de jager pl. bioRxiv [Preprint]. 2023 Apr 21:2023.02.03.527065. doi: 10.1101/2023.02.03.527065. bioRxiv. 2023. Update in: PLoS Biol. 2024 Aug 22;22(8):e3002723. doi: 10.1371/journal.pbio.3002723 PMID: 36778249 Free PMC article. Updated. Preprint.
Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease.
Seto M, Dumitrescu L, Mahoney ER, Sclafani AM, De Jager PL, Menon V, Koran MEI, Robinson RA, Ruderfer DM, Cox NJ, Seyfried NT, Jefferson AL, Schneider JA, Bennett DA, Petyuk VA, Hohman TJ. Seto M, et al. Among authors: de jager pl. Neurobiol Aging. 2023 Jun;126:25-33. doi: 10.1016/j.neurobiolaging.2023.01.010. Epub 2023 Jan 26. Neurobiol Aging. 2023. PMID: 36905877 Free PMC article.
Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings.
Sasse A, Ng B, Spiro AE, Tasaki S, Bennett DA, Gaiteri C, De Jager PL, Chikina M, Mostafavi S. Sasse A, et al. Among authors: de jager pl. bioRxiv [Preprint]. 2023 Sep 28:2023.03.16.532969. doi: 10.1101/2023.03.16.532969. bioRxiv. 2023. Update in: Nat Genet. 2023 Dec;55(12):2060-2064. doi: 10.1038/s41588-023-01524-6 PMID: 36993652 Free PMC article. Updated. Preprint.
A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis.
Zeng L, Fujita M, Gao Z, White CC, Green GS, Habib N, Menon V, Bennett DA, Boyle PA, Klein HU, De Jager PL. Zeng L, et al. Among authors: de jager pl. medRxiv [Preprint]. 2023 Mar 29:2023.03.27.23286844. doi: 10.1101/2023.03.27.23286844. medRxiv. 2023. Update in: Biol Psychiatry. 2024 Jul 1;96(1):34-43. doi: 10.1016/j.biopsych.2023.12.012 PMID: 37034737 Free PMC article. Updated. Preprint.
Psychosocial experiences are associated with human brain mitochondrial biology.
Trumpff C, Monzel AS, Sandi C, Menon V, Klein HU, Fujita M, Lee A, Petyuk VA, Hurst C, Duong DM, Seyfried NT, Wingo AP, Wingo TS, Wang Y, Thambisetty M, Ferrucci L, Bennett DA, De Jager PL, Picard M. Trumpff C, et al. Among authors: de jager pl. Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2317673121. doi: 10.1073/pnas.2317673121. Epub 2024 Jun 18. Proc Natl Acad Sci U S A. 2024. PMID: 38889126 Free PMC article.
Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's disease.
Lee H, Pearse RV, Lish AM, Pan C, Augur ZM, Terzioglu G, Gaur P, Liao M, Fujita M, Tio ES, Duong DM, Felsky D, Seyfried NT, Menon V, Bennett DA, De Jager PL, Young-Pearse TL. Lee H, et al. Among authors: de jager pl. bioRxiv [Preprint]. 2024 Jul 31:2024.07.31.605928. doi: 10.1101/2024.07.31.605928. bioRxiv. 2024. PMID: 39211227 Free PMC article. Preprint.
587 results