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Epigenetic suppression of creatine kinase B in adipocytes links endoplasmic reticulum stress to obesity-associated inflammation.
Renzi G, Vlassakev I, Hansen M, Higos R, Lecoutre S, Elmastas M, Hodek O, Moritz T, Alaeddine LM, Frendo-Cumbo S, Dahlman I, Kerr A, Maqdasy S, Mejhert N, Rydén M. Renzi G, et al. Among authors: mejhert n. Mol Metab. 2024 Dec 13;92:102082. doi: 10.1016/j.molmet.2024.102082. Online ahead of print. Mol Metab. 2024. PMID: 39675471 Free article.
Adipose tissue retains an epigenetic memory of obesity after weight loss.
Hinte LC, Castellano-Castillo D, Ghosh A, Melrose K, Gasser E, Noé F, Massier L, Dong H, Sun W, Hoffmann A, Wolfrum C, Rydén M, Mejhert N, Blüher M, von Meyenn F. Hinte LC, et al. Among authors: mejhert n. Nature. 2024 Dec;636(8042):457-465. doi: 10.1038/s41586-024-08165-7. Epub 2024 Nov 18. Nature. 2024. PMID: 39558077 Free PMC article.
Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health.
Lecoutre S, Maqdasy S, Rizo-Roca D, Renzi G, Vlassakev I, Alaeddine LM, Higos R, Jalkanen J, Zhong J, Zareifi DS, Frendo-Cumbo S, Massier L, Hodek O, Juvany M, Moritz T, de Castro Barbosa T, Omar-Hmeadi M, López-Yus M, Merabtene F, Abatan JB, Marcelin G, El Hachem EJ, Rouault C, Bergo MO, Petrus P, Zierath JR, Clément K, Krook A, Mejhert N, Rydén M. Lecoutre S, et al. Among authors: mejhert n. Nat Metab. 2024 Jul;6(7):1329-1346. doi: 10.1038/s42255-024-01083-y. Epub 2024 Jul 15. Nat Metab. 2024. PMID: 39009762 Free PMC article.
A spatiotemporal proteomic map of human adipogenesis.
Klingelhuber F, Frendo-Cumbo S, Omar-Hmeadi M, Massier L, Kakimoto P, Taylor AJ, Couchet M, Ribicic S, Wabitsch M, Messias AC, Iuso A, Müller TD, Rydén M, Mejhert N, Krahmer N. Klingelhuber F, et al. Among authors: mejhert n. Nat Metab. 2024 May;6(5):861-879. doi: 10.1038/s42255-024-01025-8. Epub 2024 Apr 2. Nat Metab. 2024. PMID: 38565923 Free PMC article.
Transcriptional determinants of lipid mobilization in human adipocytes.
Ludzki AC, Hansen M, Zareifi D, Jalkanen J, Huang Z, Omar-Hmeadi M, Renzi G, Klingelhuber F, Boland S, Ambaw YA, Wang N, Damdimopoulos A, Liu J, Jernberg T, Petrus P, Arner P, Krahmer N, Fan R, Treuter E, Gao H, Rydén M, Mejhert N. Ludzki AC, et al. Among authors: mejhert n. Sci Adv. 2024 Jan 5;10(1):eadi2689. doi: 10.1126/sciadv.adi2689. Epub 2024 Jan 3. Sci Adv. 2024. PMID: 38170777 Free PMC article.
An integrated single cell and spatial transcriptomic map of human white adipose tissue.
Massier L, Jalkanen J, Elmastas M, Zhong J, Wang T, Nono Nankam PA, Frendo-Cumbo S, Bäckdahl J, Subramanian N, Sekine T, Kerr AG, Tseng BTP, Laurencikiene J, Buggert M, Lourda M, Kublickiene K, Bhalla N, Andersson A, Valsesia A, Astrup A, Blaak EE, Ståhl PL, Viguerie N, Langin D, Wolfrum C, Blüher M, Rydén M, Mejhert N. Massier L, et al. Among authors: mejhert n. Nat Commun. 2023 Mar 15;14(1):1438. doi: 10.1038/s41467-023-36983-2. Nat Commun. 2023. PMID: 36922516 Free PMC article.
Tryptophan metabolism is a physiological integrator regulating circadian rhythms.
Petrus P, Cervantes M, Samad M, Sato T, Chao A, Sato S, Koronowski KB, Park G, Alam Y, Mejhert N, Seldin MM, Monroy Kuhn JM, Dyar KA, Lutter D, Baldi P, Kaiser P, Jang C, Sassone-Corsi P. Petrus P, et al. Among authors: mejhert n. Mol Metab. 2022 Oct;64:101556. doi: 10.1016/j.molmet.2022.101556. Epub 2022 Jul 29. Mol Metab. 2022. PMID: 35914650 Free PMC article.
76 results