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Page 1
Cell-integrated serum-induced signalling patterns can differentiate between hand and knee osteoarthritis patients.
Neefjes M, Housmans BAC, Kaffa C, Thielen NGM, Joosten LAB, van den Ende CHM, Vitters EL, van den Akker GGH, Welting TJM, van Caam APM, van der Kraan PM. Neefjes M, et al. Among authors: van caam apm. Rheumatology (Oxford). 2024 Nov 18:keae555. doi: 10.1093/rheumatology/keae555. Online ahead of print. Rheumatology (Oxford). 2024. PMID: 39558621
Systemic sclerosis-associated pulmonary arterial hypertension is characterized by a distinct peripheral T helper cell profile.
Papadimitriou TI, Lemmers JMJ, van Caam APM, Vos JL, Vitters EL, Stinissen L, van Leuven SI, Koenders MI, van der Kraan PM, Koenen HJPM, Smeets RL, Nijveldt R, Vonk MC, Thurlings RM. Papadimitriou TI, et al. Among authors: van caam apm. Rheumatology (Oxford). 2024 Sep 1;63(9):2525-2534. doi: 10.1093/rheumatology/keae190. Rheumatology (Oxford). 2024. PMID: 38552313 Free PMC article.
Separating friend from foe: Inhibition of TGF-β-induced detrimental SMAD1/5/9 phosphorylation while maintaining protective SMAD2/3 signaling in OA chondrocytes.
Thielen NGM, van Caam APM, V Beuningen HM, Vitters EL, van den Bosch MHJ, Koenders MI, van de Loo FAJ, Blaney Davidson EN, van der Kraan PM. Thielen NGM, et al. Among authors: van caam apm. Osteoarthritis Cartilage. 2023 Nov;31(11):1481-1490. doi: 10.1016/j.joca.2023.08.004. Epub 2023 Aug 29. Osteoarthritis Cartilage. 2023. PMID: 37652257 Free article.
Identification of Transcription Factors Responsible for a Transforming Growth Factor-β-Driven Hypertrophy-like Phenotype in Human Osteoarthritic Chondrocytes.
Thielen NGM, Neefjes M, Vitters EL, van Beuningen HM, Blom AB, Koenders MI, van Lent PLEM, van de Loo FAJ, Blaney Davidson EN, van Caam APM, van der Kraan PM. Thielen NGM, et al. Among authors: van caam apm. Cells. 2022 Apr 5;11(7):1232. doi: 10.3390/cells11071232. Cells. 2022. PMID: 35406794 Free PMC article.
Fibroblast Activation Protein Targeted Photodynamic Therapy Selectively Kills Activated Skin Fibroblasts from Systemic Sclerosis Patients and Prevents Tissue Contraction.
Dorst DN, van Caam APM, Vitters EL, Walgreen B, Helsen MMA, Klein C, Gudi S, Wubs T, Kumari J, Vonk MC, van der Kraan PM, Koenders MI. Dorst DN, et al. Among authors: van caam apm. Int J Mol Sci. 2021 Nov 24;22(23):12681. doi: 10.3390/ijms222312681. Int J Mol Sci. 2021. PMID: 34884484 Free PMC article.
Increased IL-6 receptor expression and signaling in ageing cartilage can be explained by loss of TGF-β-mediated IL-6 receptor suppression.
Wiegertjes R, Thielen NGM, van Caam APM, van Laar M, van Beuningen HM, Koenders MI, van Lent PLEM, van der Kraan PM, van de Loo FAJ, Blaney Davidson EN. Wiegertjes R, et al. Among authors: van caam apm. Osteoarthritis Cartilage. 2021 May;29(5):773-782. doi: 10.1016/j.joca.2021.01.008. Epub 2021 Feb 20. Osteoarthritis Cartilage. 2021. PMID: 33617971 Free article.
TGFβ/BMP Signaling Pathway in Cartilage Homeostasis.
Thielen NGM, van der Kraan PM, van Caam APM. Thielen NGM, et al. Among authors: van caam apm. Cells. 2019 Aug 24;8(9):969. doi: 10.3390/cells8090969. Cells. 2019. PMID: 31450621 Free PMC article. Review.
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