Perry JK - Search Results

1

Lack of activity of HIV-1 integrase strand-transfer inhibitors on recombinase activating gene (RAG) activity at clinically relevant concentrations.

Demirdjian S, Duong VN, Byrum JN, Nayak A, McKinney CB, Perry JK, Callebaut C, Rodgers KK, Falkard B, Feng JY. Demirdjian S, et al. Among authors: perry jk. Microbiol Spectr. 2025 Jan 7;13(1):e0246824. doi: 10.1128/spectrum.02468-24. Epub 2024 Nov 19. Microbiol Spectr. 2025. PMID: 39560443 Free PMC article.

2

Synthesis and characterization of 2'-C-Me branched C-nucleosides as HCV polymerase inhibitors.

Cho A, Zhang L, Xu J, Babusis D, Butler T, Lee R, Saunders OL, Wang T, Parrish J, Perry J, Feng JY, Ray AS, Kim CU. Cho A, et al. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4127-32. doi: 10.1016/j.bmcl.2012.04.065. Epub 2012 Apr 20. Bioorg Med Chem Lett. 2012. PMID: 22578461

3

Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.

Feng JY, Cheng G, Perry J, Barauskas O, Xu Y, Fenaux M, Eng S, Tirunagari N, Peng B, Yu M, Tian Y, Lee YJ, Stepan G, Lagpacan LL, Jin D, Hung M, Ku KS, Han B, Kitrinos K, Perron M, Birkus G, Wong KA, Zhong W, Kim CU, Carey A, Cho A, Ray AS. Feng JY, et al. Antimicrob Agents Chemother. 2014;58(4):1930-42. doi: 10.1128/AAC.02351-13. Epub 2014 Jan 13. Antimicrob Agents Chemother. 2014. PMID: 24419349 Free PMC article.

4

Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus.

Feng JY, Xu Y, Barauskas O, Perry JK, Ahmadyar S, Stepan G, Yu H, Babusis D, Park Y, McCutcheon K, Perron M, Schultz BE, Sakowicz R, Ray AS. Feng JY, et al. Among authors: perry jk. Antimicrob Agents Chemother. 2015 Nov 23;60(2):806-17. doi: 10.1128/AAC.01922-15. Print 2016 Feb. Antimicrob Agents Chemother. 2015. PMID: 26596942 Free PMC article.

5

In vitro selection of resistance to sofosbuvir in HCV replicons of genotype-1 to -6.

Xu S, Doehle B, Rajyaguru S, Han B, Barauskas O, Feng J, Perry J, Dvory-Sobol H, Svarovskaia ES, Miller MD, Mo H. Xu S, et al. Antivir Ther. 2017;22(7):587-597. doi: 10.3851/IMP3149. Epub 2017 Mar 1. Antivir Ther. 2017. PMID: 28248189

6

Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency.

Gordon CJ, Tchesnokov EP, Woolner E, Perry JK, Feng JY, Porter DP, Götte M. Gordon CJ, et al. Among authors: perry jk. J Biol Chem. 2020 May 15;295(20):6785-6797. doi: 10.1074/jbc.RA120.013679. Epub 2020 Apr 13. J Biol Chem. 2020. PMID: 32284326 Free PMC article.

7

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice.

Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH 3rd, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, Graham RL, Perry JK, Du Pont V, Pitts J, Ma B, Babusis D, Murakami E, Feng JY, Bilello JP, Porter DP, Cihlar T, Baric RS, Denison MR, Sheahan TP. Pruijssers AJ, et al. Among authors: perry jk. Cell Rep. 2020 Jul 21;32(3):107940. doi: 10.1016/j.celrep.2020.107940. Epub 2020 Jul 7. Cell Rep. 2020. PMID: 32668216 Free PMC article.

8

Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action.

Tchesnokov EP, Gordon CJ, Woolner E, Kocinkova D, Perry JK, Feng JY, Porter DP, Götte M. Tchesnokov EP, et al. Among authors: perry jk. J Biol Chem. 2020 Nov 20;295(47):16156-16165. doi: 10.1074/jbc.AC120.015720. Epub 2020 Sep 23. J Biol Chem. 2020. PMID: 32967965 Free PMC article.

9

An atomistic model of the coronavirus replication-transcription complex as a hexamer assembled around nsp15.

Perry JK, Appleby TC, Bilello JP, Feng JY, Schmitz U, Campbell EA. Perry JK, et al. J Biol Chem. 2021 Oct;297(4):101218. doi: 10.1016/j.jbc.2021.101218. Epub 2021 Sep 23. J Biol Chem. 2021. PMID: 34562452 Free PMC article.

10

Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir.

Gordon CJ, Lee HW, Tchesnokov EP, Perry JK, Feng JY, Bilello JP, Porter DP, Götte M. Gordon CJ, et al. Among authors: perry jk. J Biol Chem. 2022 Feb;298(2):101529. doi: 10.1016/j.jbc.2021.101529. Epub 2021 Dec 23. J Biol Chem. 2022. PMID: 34953856 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

118 results

Search Page

Filters