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Strategic Single-Residue Substitution in the Antimicrobial Peptide Esc(1-21) Confers Activity against Staphylococcus aureus, Including Drug-Resistant and Biofilm Phenotype.
Loffredo MR, Casciaro B, Bellavita R, Troiano C, Brancaccio D, Cappiello F, Merlino F, Galdiero S, Fabrizi G, Grieco P, Stella L, Carotenuto A, Mangoni ML. Loffredo MR, et al. ACS Infect Dis. 2024 Jul 12;10(7):2403-2418. doi: 10.1021/acsinfecdis.4c00130. Epub 2024 Jun 7. ACS Infect Dis. 2024. PMID: 38848266 Free PMC article.
The antimicrobial potential of adarotene derivatives against Staphylococcus aureus strains.
Princiotto S, Casciaro B, G Temprano A, Musso L, Sacchi F, Loffredo MR, Cappiello F, Sacco F, Raponi G, Fernandez VP, Iucci T, Mangoni ML, Mori M, Dallavalle S, Pisano C. Princiotto S, et al. Among authors: loffredo mr. Bioorg Chem. 2024 Apr;145:107227. doi: 10.1016/j.bioorg.2024.107227. Epub 2024 Feb 18. Bioorg Chem. 2024. PMID: 38387400 Free article.
The antimicrobial peptide Esc(1-21)-1c increases susceptibility of Pseudomonas aeruginosa to conventional antibiotics by decreasing the expression of the MexAB-OprM efflux pump.
Canè C, Casciaro B, Di Somma A, Loffredo MR, Puglisi E, Battaglia G, Mellini M, Cappiello F, Rampioni G, Leoni L, Amoresano A, Duilio A, Mangoni ML. Canè C, et al. Among authors: loffredo mr. Front Chem. 2023 Oct 24;11:1271153. doi: 10.3389/fchem.2023.1271153. eCollection 2023. Front Chem. 2023. PMID: 37942400 Free PMC article.
KDEON WK-11: A short antipseudomonal peptide with promising potential.
Casciaro B, Loffredo MR, Cappiello F, O'Sullivan N, Tortora C, Manzer R, Karmakar S, Haskell A, Hasan SK, Mangoni ML. Casciaro B, et al. Among authors: loffredo mr. Front Chem. 2022 Nov 17;10:1000765. doi: 10.3389/fchem.2022.1000765. eCollection 2022. Front Chem. 2022. PMID: 36465859 Free PMC article.
Pulmonary Safety Profile of Esc Peptides and Esc-Peptide-Loaded Poly(lactide-co-glycolide) Nanoparticles: A Promising Therapeutic Approach for Local Treatment of Lung Infectious Diseases.
Cappiello F, Casciaro B, Loffredo MR, Puglisi E, Lin Q, Yang D, Conte G, d'Angelo I, Ungaro F, Ferrera L, Barbieri R, Cresti L, Pini A, Di YP, Mangoni ML. Cappiello F, et al. Among authors: loffredo mr. Pharmaceutics. 2022 Oct 26;14(11):2297. doi: 10.3390/pharmaceutics14112297. Pharmaceutics. 2022. PMID: 36365116 Free PMC article.
36 results