Guo D - Search Results

1

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion.

Zhu R, Ye X, Lu X, Xiao L, Yuan M, Zhao H, Guo D, Meng Y, Han H, Luo S, Wu Q, Jiang X, Xu J, Tang Z, Tao YJ, Lu Z. Zhu R, et al. Among authors: guo d. Cell Metab. 2024 Nov 12:S1550-4131(24)00411-X. doi: 10.1016/j.cmet.2024.10.015. Online ahead of print. Cell Metab. 2024. PMID: 39561764

2

Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα.

Guo D, Tong Y, Jiang X, Meng Y, Jiang H, Du L, Wu Q, Li S, Luo S, Li M, Xiao L, He H, He X, Yu Q, Fang J, Lu Z. Guo D, et al. Cell Metab. 2022 Sep 6;34(9):1312-1324.e6. doi: 10.1016/j.cmet.2022.08.002. Epub 2022 Aug 24. Cell Metab. 2022. PMID: 36007522 Free article.

3

Determiners of cell fates: the tricarboxylic acid cycle versus the citrate-malate shuttle.

Guo D, He H, Meng Y, Luo S, Lu Z. Guo D, et al. Protein Cell. 2023 Apr 13;14(3):162-164. doi: 10.1093/procel/pwac026. Protein Cell. 2023. PMID: 37051670 Free PMC article. No abstract available.

4

Hexokinases in cancer and other pathologies.

Guo D, Meng Y, Jiang X, Lu Z. Guo D, et al. Cell Insight. 2023 Jan 3;2(1):100077. doi: 10.1016/j.cellin.2023.100077. eCollection 2023 Feb. Cell Insight. 2023. PMID: 37192912 Free PMC article. Review.

5

Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc.

Wang J, Yang Y, Shao F, Meng Y, Guo D, He J, Lu Z. Wang J, et al. Among authors: guo d. Nat Metab. 2024 May;6(5):914-932. doi: 10.1038/s42255-024-01037-4. Epub 2024 May 3. Nat Metab. 2024. PMID: 38702440

6

Glycolytic enzyme PFKL governs lipolysis by promoting lipid droplet-mitochondria tethering to enhance β-oxidation and tumor cell proliferation.

Meng Y, Guo D, Lin L, Zhao H, Xu W, Luo S, Jiang X, Li S, He X, Zhu R, Shi R, Xiao L, Wu Q, He H, Tao J, Jiang H, Wang Z, Yao P, Xu D, Lu Z. Meng Y, et al. Among authors: guo d. Nat Metab. 2024 Jun;6(6):1092-1107. doi: 10.1038/s42255-024-01047-2. Epub 2024 May 21. Nat Metab. 2024. PMID: 38773347

7

Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth.

Wang Z, Li M, Jiang H, Luo S, Shao F, Xia Y, Yang M, Ren X, Liu T, Yan M, Qian X, He H, Guo D, Duan Y, Wu K, Wang L, Ji G, Shen Y, Li L, Zheng P, Dong B, Fang J, Zheng M, Liang T, Li H, Yu R, Xu D, Lu Z. Wang Z, et al. Among authors: guo d. Nat Cell Biol. 2022 Nov;24(11):1655-1665. doi: 10.1038/s41556-022-01009-4. Epub 2022 Oct 20. Nat Cell Biol. 2022. PMID: 36266488

8

Fructose-1,6-bisphosphatase 1 dephosphorylates and inhibits TERT for tumor suppression.

Li M, Wang Z, Tao J, Jiang H, Yang H, Guo D, Zhao H, He X, Luo S, Jiang X, Yuan L, Xiao L, He H, Yu R, Fang J, Liang T, Mao Z, Xu D, Lu Z. Li M, et al. Among authors: guo d. Nat Chem Biol. 2024 Nov;20(11):1505-1513. doi: 10.1038/s41589-024-01597-2. Epub 2024 Mar 27. Nat Chem Biol. 2024. PMID: 38538923

9

KAT2A succinyltransferase activity-mediated 14-3-3ζ upregulation promotes β-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cells.

Tong Y, Guo D, Yan D, Ma C, Shao F, Wang Y, Luo S, Lin L, Tao J, Jiang Y, Lu Z, Xing D. Tong Y, et al. Among authors: guo d. Cancer Lett. 2020 Jan 28;469:1-10. doi: 10.1016/j.canlet.2019.09.015. Epub 2019 Oct 11. Cancer Lett. 2020. PMID: 31610265

10

Silencing EGFR-upregulated expression of CD55 and CD59 activates the complement system and sensitizes lung cancer to checkpoint blockade.

Shao F, Gao Y, Wang W, He H, Xiao L, Geng X, Xia Y, Guo D, Fang J, He J, Lu Z. Shao F, et al. Among authors: guo d. Nat Cancer. 2022 Oct;3(10):1192-1210. doi: 10.1038/s43018-022-00444-4. Epub 2022 Oct 21. Nat Cancer. 2022. PMID: 36271172

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