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Breathing new insights into the role of mutant p53 in lung cancer.
Chen T, Ashwood LM, Kondrashova O, Strasser A, Kelly G, Sutherland KD. Chen T, et al. Among authors: strasser a. Oncogene. 2025 Feb;44(3):115-129. doi: 10.1038/s41388-024-03219-6. Epub 2024 Nov 20. Oncogene. 2025. PMID: 39567755 Free PMC article. Review.
The essential role of evasion from cell death in cancer.
Kelly GL, Strasser A. Kelly GL, et al. Among authors: strasser a. Adv Cancer Res. 2011;111:39-96. doi: 10.1016/B978-0-12-385524-4.00002-7. Adv Cancer Res. 2011. PMID: 21704830 Free PMC article. Review.
The detection of genetic lesions in human cancers that activate prosurvival genes or disable proapoptotic genes have provided the first evidence that defects in programmed cell death can cause cancer (Tagawa et al., 2005; Tsujimoto et al., 1984; Vaux, Cory, and Adams, 1988) and t …
The detection of genetic lesions in human cancers that activate prosurvival genes or disable proapoptotic genes have provided the first evid …
Should mutant TP53 be targeted for cancer therapy?
Wang Z, Strasser A, Kelly GL. Wang Z, et al. Among authors: strasser a. Cell Death Differ. 2022 May;29(5):911-920. doi: 10.1038/s41418-022-00962-9. Epub 2022 Mar 24. Cell Death Differ. 2022. PMID: 35332311 Free PMC article. Review.
The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells.
Wang Z, Hu H, Heitink L, Rogers K, You Y, Tan T, Suen CLW, Garnham A, Chen H, Lieschke E, Diepstraten ST, Chang C, Chen T, Moujalled D, Sutherland K, Lessene G, Sieber OM, Visvader J, Kelly GL, Strasser A. Wang Z, et al. Among authors: strasser a. Cell Death Differ. 2023 Apr;30(4):1033-1046. doi: 10.1038/s41418-023-01122-3. Epub 2023 Feb 4. Cell Death Differ. 2023. PMID: 36739334 Free PMC article.
BCL-W makes only minor contributions to MYC-driven lymphoma development.
Diepstraten ST, La Marca JE, Chang C, Young S, Strasser A, Kelly GL. Diepstraten ST, et al. Among authors: strasser a. Oncogene. 2023 Sep;42(37):2776-2781. doi: 10.1038/s41388-023-02804-5. Epub 2023 Aug 11. Oncogene. 2023. PMID: 37567974 Free PMC article.
Tumor-Suppressor Functions of the TP53 Pathway.
Aubrey BJ, Strasser A, Kelly GL. Aubrey BJ, et al. Among authors: strasser a. Cold Spring Harb Perspect Med. 2016 May 2;6(5):a026062. doi: 10.1101/cshperspect.a026062. Cold Spring Harb Perspect Med. 2016. PMID: 27141080 Free PMC article. Review.
Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis.
Best SA, Vandenberg CJ, Abad E, Whitehead L, Guiu L, Ding S, Brennan MS, Strasser A, Herold MJ, Sutherland KD, Janic A. Best SA, et al. Among authors: strasser a. Cell Death Dis. 2020 Oct 20;11(10):877. doi: 10.1038/s41419-020-03066-9. Cell Death Dis. 2020. PMID: 33082333 Free PMC article.
913 results