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Discovery of GS-2278, a Potent and Selective LPAR1 Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis.
J Med Chem. 2024 Nov 21. doi: 10.1021/acs.jmedchem.4c02090. Online ahead of print.
J Med Chem. 2024.
PMID: 39570661
molli: A General Purpose Python Toolkit for Combinatorial Small Molecule Library Generation, Manipulation, and Feature Extraction.
Shved AS, Ocampo BE, Burlova ES, Olen CL, Rinehart NI, Denmark SE.
Shved AS, et al. Among authors: olen cl.
J Chem Inf Model. 2024 Nov 11;64(21):8083-8090. doi: 10.1021/acs.jcim.4c00424. Epub 2024 Oct 23.
J Chem Inf Model. 2024.
PMID: 39441186
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A Unified Strategy for the Asymmetric Synthesis of Highly Substituted 1,2-Amino Alcohols Leading to Highly Substituted Bisoxazoline Ligands.
Shrestha B, Rose BT, Olen CL, Roth A, Kwong AC, Wang Y, Denmark SE.
Shrestha B, et al. Among authors: olen cl.
J Org Chem. 2021 Feb 19;86(4):3490-3534. doi: 10.1021/acs.joc.0c02899. Epub 2021 Feb 4.
J Org Chem. 2021.
PMID: 33539091
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Ruthenium-Catalyzed Hydroamination of Unactivated Terminal Alkenes with Stoichiometric Amounts of Alkene and an Ammonia Surrogate by Sequential Oxidation and Reduction.
Ma S, Hill CK, Olen CL, Hartwig JF.
Ma S, et al. Among authors: olen cl.
J Am Chem Soc. 2021 Jan 13;143(1):359-368. doi: 10.1021/jacs.0c11043. Epub 2020 Dec 24.
J Am Chem Soc. 2021.
PMID: 33356181
Free PMC article.
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