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Deep generative AI models analyzing circulating orphan non-coding RNAs enable detection of early-stage lung cancer.
Karimzadeh M, Momen-Roknabadi A, Cavazos TB, Fang Y, Chen NC, Multhaup M, Yen J, Ku J, Wang J, Zhao X, Murzynowski P, Wang K, Hanna R, Huang A, Corti D, Nguyen D, Lam T, Kilinc S, Arensdorf P, Chau KH, Hartwig A, Fish L, Li H, Behsaz B, Elemento O, Zou J, Hormozdiari F, Alipanahi B, Goodarzi H. Karimzadeh M, et al. Among authors: hormozdiari f. Nat Commun. 2024 Nov 21;15(1):10090. doi: 10.1038/s41467-024-53851-9. Nat Commun. 2024. PMID: 39572521 Free PMC article.
Unsupervised representation learning on high-dimensional clinical data improves genomic discovery and prediction.
Yun T, Cosentino J, Behsaz B, McCaw ZR, Hill D, Luben R, Lai D, Bates J, Yang H, Schwantes-An TH, Zhou Y, Khawaja AP, Carroll A, Hobbs BD, Cho MH, McLean CY, Hormozdiari F. Yun T, et al. Among authors: hormozdiari f. Nat Genet. 2024 Aug;56(8):1604-1613. doi: 10.1038/s41588-024-01831-6. Epub 2024 Jul 8. Nat Genet. 2024. PMID: 38977853 Free PMC article.
Utilizing multimodal AI to improve genetic analyses of cardiovascular traits.
Zhou Y, Cosentino J, Yun T, Biradar MI, Shreibati J, Lai D, Schwantes-An TH, Luben R, McCaw Z, Engmann J, Providencia R, Schmidt AF, Munroe P, Yang H, Carroll A, Khawaja AP, McLean CY, Behsaz B, Hormozdiari F. Zhou Y, et al. Among authors: hormozdiari f. medRxiv [Preprint]. 2024 Mar 20:2024.03.19.24304547. doi: 10.1101/2024.03.19.24304547. medRxiv. 2024. PMID: 38562791 Free PMC article. Preprint.
Unsupervised representation learning improves genomic discovery and risk prediction for respiratory and circulatory functions and diseases.
Yun T, Cosentino J, Behsaz B, McCaw ZR, Hill D, Luben R, Lai D, Bates J, Yang H, Schwantes-An TH, Zhou Y, Khawaja AP, Carroll A, Hobbs BD, Cho MH, McLean CY, Hormozdiari F. Yun T, et al. Among authors: hormozdiari f. medRxiv [Preprint]. 2023 Aug 29:2023.04.28.23289285. doi: 10.1101/2023.04.28.23289285. medRxiv. 2023. Update in: Nat Genet. 2024 Aug;56(8):1604-1613. doi: 10.1038/s41588-024-01831-6 PMID: 37163049 Free PMC article. Updated. Preprint.
MAGI-MS: multiple seed-centric module discovery.
Chow JC, Zhou R, Hormozdiari F. Chow JC, et al. Among authors: hormozdiari f. Bioinform Adv. 2022 Apr 29;2(1):vbac025. doi: 10.1093/bioadv/vbac025. eCollection 2022. Bioinform Adv. 2022. PMID: 36699383 Free PMC article.
High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios.
Byrska-Bishop M, Evani US, Zhao X, Basile AO, Abel HJ, Regier AA, Corvelo A, Clarke WE, Musunuri R, Nagulapalli K, Fairley S, Runnels A, Winterkorn L, Lowy E; Human Genome Structural Variation Consortium; Paul Flicek, Germer S, Brand H, Hall IM, Talkowski ME, Narzisi G, Zody MC. Byrska-Bishop M, et al. Cell. 2022 Sep 1;185(18):3426-3440.e19. doi: 10.1016/j.cell.2022.08.004. Cell. 2022. PMID: 36055201 Free PMC article.
157 results