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Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection.
Alcorn MDH, Sun C, Gilliland TC Jr, Lukash T, Crasto CM, Raju S, Diamond MS, Weaver SC, Klimstra WB. Alcorn MDH, et al. Among authors: gilliland tc jr. bioRxiv [Preprint]. 2024 Nov 4:2024.11.04.621500. doi: 10.1101/2024.11.04.621500. bioRxiv. 2024. PMID: 39574633 Free PMC article. Preprint.
Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope.
Kim AS, Kafai NM, Winkler ES, Gilliland TC Jr, Cottle EL, Earnest JT, Jethva PN, Kaplonek P, Shah AP, Fong RH, Davidson E, Malonis RJ, Quiroz JA, Williamson LE, Vang L, Mack M, Crowe JE Jr, Doranz BJ, Lai JR, Alter G, Gross ML, Klimstra WB, Fremont DH, Diamond MS. Kim AS, et al. Among authors: gilliland tc jr. Cell. 2021 Aug 19;184(17):4414-4429.e19. doi: 10.1016/j.cell.2021.07.006. Cell. 2021. PMID: 34416146 Free PMC article.