Sun C - Search Results

1

Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection.

Alcorn MDH, Sun C, Gilliland TC Jr, Lukash T, Crasto CM, Raju S, Diamond MS, Weaver SC, Klimstra WB. Alcorn MDH, et al. Among authors: sun c. bioRxiv [Preprint]. 2024 Nov 4:2024.11.04.621500. doi: 10.1101/2024.11.04.621500. bioRxiv. 2024. PMID: 39574633 Free PMC article. Preprint.

2

Natural variation in the heparan sulfate binding domain of the eastern equine encephalitis virus E2 glycoprotein alters interactions with cell surfaces and virulence in mice.

Gardner CL, Choi-Nurvitadhi J, Sun C, Bayer A, Hritz J, Ryman KD, Klimstra WB. Gardner CL, et al. Among authors: sun c. J Virol. 2013 Aug;87(15):8582-90. doi: 10.1128/JVI.00937-13. Epub 2013 May 29. J Virol. 2013. PMID: 23720725 Free PMC article.

3

Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein.

Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE Jr, Slifka MK, Fremont DH, Klimstra WB, Diamond MS. Kim AS, et al. Among authors: sun c. Nat Microbiol. 2019 Jan;4(1):187-197. doi: 10.1038/s41564-018-0286-4. Epub 2018 Nov 19. Nat Microbiol. 2019. PMID: 30455470 Free PMC article.

4

Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.

Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG. Hasan SS, et al. Among authors: sun c. Cell Rep. 2018 Dec 11;25(11):3136-3147.e5. doi: 10.1016/j.celrep.2018.11.067. Cell Rep. 2018. PMID: 30540945 Free PMC article.

5

Rational design of a live-attenuated eastern equine encephalitis virus vaccine through informed mutation of virulence determinants.

Trobaugh DW, Sun C, Dunn MD, Reed DS, Klimstra WB. Trobaugh DW, et al. Among authors: sun c. PLoS Pathog. 2019 Feb 11;15(2):e1007584. doi: 10.1371/journal.ppat.1007584. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30742691 Free PMC article.

6

Cooperativity between the 3' untranslated region microRNA binding sites is critical for the virulence of eastern equine encephalitis virus.

Trobaugh DW, Sun C, Bhalla N, Gardner CL, Dunn MD, Klimstra WB. Trobaugh DW, et al. Among authors: sun c. PLoS Pathog. 2019 Oct 28;15(10):e1007867. doi: 10.1371/journal.ppat.1007867. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31658290 Free PMC article.

7

Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues.

Chen CL, Hasan SS, Klose T, Sun Y, Buda G, Sun C, Klimstra WB, Rossmann MG. Chen CL, et al. Among authors: sun c, sun y. Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):8890-8899. doi: 10.1073/pnas.1910670117. Epub 2020 Apr 3. Proc Natl Acad Sci U S A. 2020. PMID: 32245806 Free PMC article.

8

SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected, hospitalized COVID-19 patients.

Klimstra WB, Tilston-Lunel NL, Nambulli S, Boslett J, McMillen CM, Gilliland T, Dunn MD, Sun C, Wheeler SE, Wells A, Hartman AL, McElroy AK, Reed DS, Rennick LJ, Duprex WP. Klimstra WB, et al. Among authors: sun c. bioRxiv [Preprint]. 2020 Jun 22:2020.06.19.154930. doi: 10.1101/2020.06.19.154930. bioRxiv. 2020. Update in: J Gen Virol. 2020 Nov;101(11):1156-1169. doi: 10.1099/jgv.0.001481 PMID: 32607507 Free PMC article. Updated. Preprint.

9

LDLRAD3 is a receptor for Venezuelan equine encephalitis virus.

Ma H, Kim AS, Kafai NM, Earnest JT, Shah AP, Case JB, Basore K, Gilliland TC, Sun C, Nelson CA, Thackray LB, Klimstra WB, Fremont DH, Diamond MS. Ma H, et al. Among authors: sun c. Nature. 2020 Dec;588(7837):308-314. doi: 10.1038/s41586-020-2915-3. Epub 2020 Nov 18. Nature. 2020. PMID: 33208938 Free PMC article.

10

Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states.

Chen CL, Klose T, Sun C, Kim AS, Buda G, Rossmann MG, Diamond MS, Klimstra WB, Kuhn RJ. Chen CL, et al. Among authors: sun c. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2114119119. doi: 10.1073/pnas.2114119119. Epub 2022 Jul 22. Proc Natl Acad Sci U S A. 2022. PMID: 35867819 Free PMC article.

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