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Bispecific CAR T Cells against EpCAM and Inducible ICAM-1 Overcome Antigen Heterogeneity and Generate Superior Antitumor Responses.
Yang Y, McCloskey JE, Yang H, Puc J, Alcaina Y, Vedvyas Y, Gomez Gallegos AA, Ortiz-Sánchez E, de Stanchina E, Min IM, von Hofe E, Jin MM. Yang Y, et al. Among authors: yang h. Cancer Immunol Res. 2021 Oct;9(10):1158-1174. doi: 10.1158/2326-6066.CIR-21-0062. Epub 2021 Aug 2. Cancer Immunol Res. 2021. PMID: 34341066 Free PMC article.
Inducible expression of interleukin-12 augments the efficacy of affinity-tuned chimeric antigen receptors in murine solid tumor models.
Yang Y, Yang H, Alcaina Y, Puc J, Birt A, Vedvyas Y, Gallagher M, Alla S, Riascos MC, McCloskey JE, Du K, Gonzalez-Valdivieso J, Min IM, de Stanchina E, Britz M, von Hofe E, Jin MM. Yang Y, et al. Among authors: yang h. Nat Commun. 2023 Apr 12;14(1):2068. doi: 10.1038/s41467-023-37646-y. Nat Commun. 2023. PMID: 37045815 Free PMC article.
PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer.
Gray KD, McCloskey JE, Vedvyas Y, Kalloo OR, Eshaky SE, Yang Y, Shevlin E, Zaman M, Ullmann TM, Liang H, Stefanova D, Christos PJ, Scognamiglio T, Tassler AB, Zarnegar R, Fahey TJ 3rd, Jin MM, Min IM. Gray KD, et al. Among authors: yang y. Clin Cancer Res. 2020 Nov 15;26(22):6003-6016. doi: 10.1158/1078-0432.CCR-20-1523. Epub 2020 Sep 4. Clin Cancer Res. 2020. PMID: 32887724 Free PMC article.
Chimeric Antigen Receptor T Cell Therapy Targeting ICAM-1 in Gastric Cancer.
Jung M, Yang Y, McCloskey JE, Zaman M, Vedvyas Y, Zhang X, Stefanova D, Gray KD, Min IM, Zarnegar R, Choi YY, Cheong JH, Noh SH, Rha SY, Chung HC, Jin MM. Jung M, et al. Among authors: yang y. Mol Ther Oncolytics. 2020 Aug 21;18:587-601. doi: 10.1016/j.omto.2020.08.009. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32995483 Free PMC article.
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