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Proteomic analysis of non-muscle invasive and muscle invasive bladder cancer highlights distinct subgroups with metabolic, matrisomal, and immune hallmarks and emphasizes importance of the stromal compartment.
Dinh TJ, Rogg M, Cosenza-Contreras M, Li M, Zirngibl M, Pinter N, Kurowski K, Hause F, Pauli L, Imberg F, Huynh A, Schmid M, Glavinsky I, Braun L, Van Wymersch C, Bergmann L, Ungefug X, Kunz M, Werner T, Bernhard P, Espadas G, Brombacher E, Schueler J, Sabido E, Kreutz C, Gratzke C, Werner M, Grabbert M, Bronsert P, Schell C, Schilling O. Dinh TJ, et al. Among authors: espadas g. J Pathol. 2025 Jan;265(1):41-56. doi: 10.1002/path.6367. Epub 2024 Nov 25. J Pathol. 2025. PMID: 39582373 Free PMC article.
Quantitative proteome analysis of LAP1-deficient human fibroblasts: A pilot approach for predicting the signaling pathways deregulated in LAP1-associated diseases.
Pereira CD, Espadas G, Martins F, Bertrand AT, Servais L, Sabidó E, Chevalier P, da Cruz E Silva OAB, Rebelo S. Pereira CD, et al. Among authors: espadas g. Biochem Biophys Rep. 2024 Jun 26;39:101757. doi: 10.1016/j.bbrep.2024.101757. eCollection 2024 Sep. Biochem Biophys Rep. 2024. PMID: 39035020 Free PMC article.
Expression of NORAD correlates with breast cancer aggressiveness and protects breast cancer cells from chemotherapy.
Alves-Vale C, Capela AM, Tavares-Marcos C, Domingues-Silva B, Pereira B, Santos F, Gomes CP, Espadas G, Vitorino R, Sabidó E, Borralho P, Nóbrega-Pereira S, Bernardes de Jesus B. Alves-Vale C, et al. Among authors: espadas g. Mol Ther Nucleic Acids. 2023 Aug 18;33:910-924. doi: 10.1016/j.omtn.2023.08.019. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37680988 Free PMC article.
Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.
Milenkovic I, Santos Vieira HG, Lucas MC, Ruiz-Orera J, Patone G, Kesteven S, Wu J, Feneley M, Espadas G, Sabidó E, Hübner N, van Heesch S, Völkers M, Novoa EM. Milenkovic I, et al. Among authors: espadas g. Nucleic Acids Res. 2023 Jun 23;51(11):5301-5324. doi: 10.1093/nar/gkad121. Nucleic Acids Res. 2023. PMID: 36882085 Free PMC article.
High-performance nano-flow liquid chromatography column combined with high- and low-collision energy data-independent acquisition enables targeted and discovery identification of modified ribonucleotides by mass spectrometry.
Espadas G, Morales-Sanfrutos J, Medina R, Lucas MC, Novoa EM, Sabidó E. Espadas G, et al. J Chromatogr A. 2022 Feb 22;1665:462803. doi: 10.1016/j.chroma.2022.462803. Epub 2022 Jan 2. J Chromatogr A. 2022. PMID: 35042139 Free article.
The loss of DHX15 impairs endothelial energy metabolism, lymphatic drainage and tumor metastasis in mice.
Ribera J, Portolés I, Córdoba-Jover B, Rodríguez-Vita J, Casals G, González-de la Presa B, Graupera M, Solsona-Vilarrasa E, Garcia-Ruiz C, Fernández-Checa JC, Soria G, Tudela R, Esteve-Codina A, Espadas G, Sabidó E, Jiménez W, Sessa WC, Morales-Ruiz M. Ribera J, et al. Among authors: espadas g. Commun Biol. 2021 Oct 15;4(1):1192. doi: 10.1038/s42003-021-02722-w. Commun Biol. 2021. PMID: 34654883 Free PMC article.
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