Petrov DA - Search Results

1

Cancers adapt to their mutational load by buffering protein misfolding stress.

Tilk S, Frydman J, Curtis C, Petrov DA. Tilk S, et al. Among authors: petrov da. Elife. 2024 Nov 25;12:RP87301. doi: 10.7554/eLife.87301. Elife. 2024. PMID: 39585785 Free PMC article.

2

More effective drugs lead to harder selective sweeps in the evolution of drug resistance in HIV-1.

Feder AF, Rhee SY, Holmes SP, Shafer RW, Petrov DA, Pennings PS. Feder AF, et al. Among authors: petrov da. Elife. 2016 Feb 15;5:e10670. doi: 10.7554/eLife.10670. Elife. 2016. PMID: 26882502 Free PMC article.

3

Viruses are a dominant driver of protein adaptation in mammals.

Enard D, Cai L, Gwennap C, Petrov DA. Enard D, et al. Among authors: petrov da. Elife. 2016 May 17;5:e12469. doi: 10.7554/eLife.12469. Elife. 2016. PMID: 27187613 Free PMC article.

4

Deep sequencing of natural and experimental populations of Drosophila melanogaster reveals biases in the spectrum of new mutations.

Assaf ZJ, Tilk S, Park J, Siegal ML, Petrov DA. Assaf ZJ, et al. Among authors: petrov da. Genome Res. 2017 Dec;27(12):1988-2000. doi: 10.1101/gr.219956.116. Epub 2017 Oct 27. Genome Res. 2017. PMID: 29079675 Free PMC article.

5

Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice.

Rogers ZN, McFarland CD, Winters IP, Seoane JA, Brady JJ, Yoon S, Curtis C, Petrov DA, Winslow MM. Rogers ZN, et al. Among authors: petrov da. Nat Genet. 2018 Apr;50(4):483-486. doi: 10.1038/s41588-018-0083-2. Epub 2018 Apr 2. Nat Genet. 2018. PMID: 29610476 Free PMC article.

6

Accurate Allele Frequencies from Ultra-low Coverage Pool-Seq Samples in Evolve-and-Resequence Experiments.

Tilk S, Bergland A, Goodman A, Schmidt P, Petrov D, Greenblum S. Tilk S, et al. G3 (Bethesda). 2019 Dec 3;9(12):4159-4168. doi: 10.1534/g3.119.400755. G3 (Bethesda). 2019. PMID: 31636085 Free PMC article.

7

Fitness variation across subtle environmental perturbations reveals local modularity and global pleiotropy of adaptation.

Kinsler G, Geiler-Samerotte K, Petrov DA. Kinsler G, et al. Among authors: petrov da. Elife. 2020 Dec 2;9:e61271. doi: 10.7554/eLife.61271. Elife. 2020. PMID: 33263280 Free PMC article.

8

The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.

Chaikovsky AC, Li C, Jeng EE, Loebell S, Lee MC, Murray CW, Cheng R, Demeter J, Swaney DL, Chen SH, Newton BW, Johnson JR, Drainas AP, Shue YT, Seoane JA, Srinivasan P, He A, Yoshida A, Hipkins SQ, McCrea E, Poltorack CD, Krogan NJ, Diehl JA, Kong C, Jackson PK, Curtis C, Petrov DA, Bassik MC, Winslow MM, Sage J. Chaikovsky AC, et al. Among authors: petrov da. Nature. 2021 Apr;592(7856):794-798. doi: 10.1038/s41586-021-03474-7. Epub 2021 Apr 14. Nature. 2021. PMID: 33854239 Free PMC article.

9

The cis-regulatory effects of modern human-specific variants.

Weiss CV, Harshman L, Inoue F, Fraser HB, Petrov DA, Ahituv N, Gokhman D. Weiss CV, et al. Among authors: petrov da. Elife. 2021 Apr 22;10:e63713. doi: 10.7554/eLife.63713. Elife. 2021. PMID: 33885362 Free PMC article.

10

Functional biology in its natural context: A search for emergent simplicity.

Bergelson J, Kreitman M, Petrov DA, Sanchez A, Tikhonov M. Bergelson J, et al. Among authors: petrov da. Elife. 2021 Jun 7;10:e67646. doi: 10.7554/eLife.67646. Elife. 2021. PMID: 34096867 Free PMC article.

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