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Inhibiting the NADase CD38 improves cytomegalovirus-specific CD8+ T cell functionality and metabolism.
Mülling N, Behr FM, Heieis GA, Boss K, van Duikeren S, van Haften FJ, Pardieck IN, van der Gracht ET, Vleeshouwers W, van der Sluis TC, de Graaf JF, Veerkamp DM, Franken KL, Lei X, van de Sand L, van der Burg SH, Welters MJ, Heidt S, Huisman W, Jochems SP, Giera M, Witzke O, de Vries AP, Kribben A, Everts B, Wilde B, Arens R. Mülling N, et al. J Clin Invest. 2024 Jul 2;134(17):e179561. doi: 10.1172/JCI179561. J Clin Invest. 2024. PMID: 38954588 Free PMC article.
A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection.
Pardieck IN, van der Sluis TC, van der Gracht ETI, Veerkamp DMB, Behr FM, van Duikeren S, Beyrend G, Rip J, Nadafi R, Beyranvand Nejad E, Mülling N, Brasem DJ, Camps MGM, Myeni SK, Bredenbeek PJ, Kikkert M, Kim Y, Cicin-Sain L, Abdelaal T, van Gisbergen KPJM, Franken KLMC, Drijfhout JW, Melief CJM, Zondag GCM, Ossendorp F, Arens R. Pardieck IN, et al. Among authors: mulling n. Nat Commun. 2022 Jul 8;13(1):3966. doi: 10.1038/s41467-022-31721-6. Nat Commun. 2022. PMID: 35803932 Free PMC article.
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