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Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer.
Sci Signal. 2024 Nov 26;17(864):eadp1375. doi: 10.1126/scisignal.adp1375. Epub 2024 Nov 26.
Sci Signal. 2024.
PMID: 39591412
TFE3-Splicing Factor Fusions Represent Functional Drivers and Druggable Targets in Translocation Renal Cell Carcinoma.
Damayanti NP, Cordova RA, Rupert C, Delle Fontane I, Shen L, Orsi S, Klunk AJ, Linehan WM, Staschke KA, Hollenhorst PC, Heppner DE, Pili R.
Damayanti NP, et al. Among authors: klunk aj.
Cancer Res. 2024 Apr 15;84(8):1286-1302. doi: 10.1158/0008-5472.CAN-23-1789.
Cancer Res. 2024.
PMID: 38266162
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Activation of the integrated stress response (ISR) pathways in response to Ref-1 inhibition in human pancreatic cancer and its tumor microenvironment.
Mijit M, Boner M, Cordova RA, Gampala S, Kpenu E, Klunk AJ, Zhang C, Kelley MR, Staschke KA, Fishel ML.
Mijit M, et al. Among authors: klunk aj.
Front Med (Lausanne). 2023 Apr 27;10:1146115. doi: 10.3389/fmed.2023.1146115. eCollection 2023.
Front Med (Lausanne). 2023.
PMID: 37181357
Free PMC article.
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GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis.
Cordova RA, Misra J, Amin PH, Klunk AJ, Damayanti NP, Carlson KR, Elmendorf AJ, Kim HG, Mirek ET, Elzey BD, Miller MJ, Dong XC, Cheng L, Anthony TG, Pili R, Wek RC, Staschke KA.
Cordova RA, et al. Among authors: klunk aj.
Elife. 2022 Sep 15;11:e81083. doi: 10.7554/eLife.81083.
Elife. 2022.
PMID: 36107759
Free PMC article.
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