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Bisphenol A single and repeated treatment increases HDAC2, leading to cholinergic neurotransmission dysfunction and SN56 cholinergic apoptotic cell death through AChE variants overexpression and NGF/TrkA/P75NTR signaling disruption.
Moyano P, Flores A, García J, García JM, Anadon MJ, Frejo MT, Sola E, Pelayo A, Del Pino J. Moyano P, et al. Among authors: flores a. Food Chem Toxicol. 2021 Nov;157:112614. doi: 10.1016/j.fct.2021.112614. Epub 2021 Oct 14. Food Chem Toxicol. 2021. PMID: 34655688
Insulin Signaling Disruption and INF-γ Upregulation Induce Aβ1-42 and Hyperphosphorylated-Tau Proteins Synthesis and Cell Death after Paraquat Treatment of Primary Hippocampal Cells.
Abascal ML, Sanjuan J, Moyano P, Sola E, Flores A, Garcia JM, Garcia J, Frejo MT, Del Pino J. Abascal ML, et al. Among authors: flores a. Chem Res Toxicol. 2022 Dec 19;35(12):2214-2218. doi: 10.1021/acs.chemrestox.2c00278. Epub 2022 Nov 17. Chem Res Toxicol. 2022. PMID: 36394833 Free PMC article.
Cadmium-promoted thyroid hormones disruption mediates ROS, inflammation, Aβ and Tau proteins production, gliosis, spongiosis and neurodegeneration in rat basal forebrain.
Sola E, Moyano P, Flores A, García JM, García J, Anadon MJ, Frejo MT, Pelayo A, de la Cabeza Fernandez M, Del Pino J. Sola E, et al. Among authors: flores a. Chem Biol Interact. 2023 Apr 25;375:110428. doi: 10.1016/j.cbi.2023.110428. Epub 2023 Mar 1. Chem Biol Interact. 2023. PMID: 36868496 Free article.
Chlorpyrifos induces cell proliferation in MCF-7 and MDA-MB-231 cells, through cholinergic and Wnt/β-catenin signaling disruption, AChE-R upregulation and oxidative stress generation after single and repeated treatment.
Moyano P, García JM, García J, Pelayo A, Muñoz-Calero P, Frejo MT, Anadon MJ, Naval MV, Flores A, Mirat VA, Del Pino J. Moyano P, et al. Among authors: flores a. Food Chem Toxicol. 2021 Jun;152:112241. doi: 10.1016/j.fct.2021.112241. Epub 2021 Apr 27. Food Chem Toxicol. 2021. PMID: 33930485
Aryl Hydrocarbon Receptor Activation Produces Heat Shock Protein 90 and 70 Overexpression, Prostaglandin E2/Wnt/β-Catenin Signaling Disruption, and Cell Proliferation in MCF-7 and MDA-MB-231 Cells after 24 h and 14 Days of Chlorpyrifos Treatment.
Moyano P, Garcia JM, García J, Pelayo A, Muñoz-Calero P, Frejo MT, Flores A, Del Pino J. Moyano P, et al. Among authors: flores a. Chem Res Toxicol. 2021 Sep 20;34(9):2019-2023. doi: 10.1021/acs.chemrestox.1c00258. Epub 2021 Aug 23. Chem Res Toxicol. 2021. PMID: 34424684 Free PMC article.
1,600 results