Li XY - Search Results

1

Corrigendum to "Novel deoxyhypusine synthase (DHPS) inhibitors target hypusination-induced vasculogenic mimicry (VM) against malignant melanoma" Pharmacol. Res. 209 (November) (2024) 107453.

Zhao XH, Ma J, Guo JS, Liu KL, Qin YX, Li LT, Zhang JF, Yang YY, Zhang SC, Meng FH, Liu L, Yang YH, Li XY. Zhao XH, et al. Among authors: li xy, li lt. Pharmacol Res. 2024 Dec;210:107523. doi: 10.1016/j.phrs.2024.107523. Epub 2024 Nov 26. Pharmacol Res. 2024. PMID: 39603849 Free article. No abstract available.

2

Novel deoxyhypusine synthase (DHPS) inhibitors target hypusination-induced vasculogenic mimicry (VM) against malignant melanoma.

Zhao XH, Ma J, Guo JS, Liu KL, Qin YX, Li LT, Zhang JF, Yang YY, Zhang SC, Meng FH, Liu L, Yang YH, Li XY. Zhao XH, et al. Among authors: li xy, li lt. Pharmacol Res. 2024 Nov;209:107453. doi: 10.1016/j.phrs.2024.107453. Epub 2024 Oct 10. Pharmacol Res. 2024. PMID: 39393437 Free article.

3

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation.

Liu KL, Li XY, Wang DP, Xue WH, Qian XH, Li YH, Lin QQ, Li S, Meng FH. Liu KL, et al. Among authors: li yh, li s, li xy. J Med Chem. 2021 Sep 23;64(18):13356-13372. doi: 10.1021/acs.jmedchem.1c00582. Epub 2021 Sep 2. J Med Chem. 2021. PMID: 34473510

4

Hypusination-induced DHPS/eIF5A pathway as a new therapeutic strategy for human diseases: A mechanistic review and structural classification of DHPS inhibitors.

Guo JS, Liu KL, Qin YX, Hou L, Jian LY, Yang YH, Li XY. Guo JS, et al. Among authors: li xy. Biomed Pharmacother. 2023 Nov;167:115440. doi: 10.1016/j.biopha.2023.115440. Epub 2023 Sep 8. Biomed Pharmacother. 2023. PMID: 37683595 Free article. Review.

5

DHPS-Mediated Hypusination Regulates METTL3 Self-m6A-Methylation Modification to Promote Melanoma Proliferation and the Development of Novel Inhibitors.

Guo JS, Ma J, Zhao XH, Zhang JF, Liu KL, Li LT, Qin YX, Meng FH, Jian LY, Yang YH, Li XY. Guo JS, et al. Among authors: li xy, li lt. Adv Sci (Weinh). 2024 Sep;11(33):e2402450. doi: 10.1002/advs.202402450. Epub 2024 Jul 1. Adv Sci (Weinh). 2024. PMID: 38952061 Free PMC article.

6

Development of a novel thymidylate synthase (TS) inhibitor capable of up-regulating P53 expression and inhibiting angiogenesis in NSCLC.

Li XY, Wang DP, Lu GQ, Liu KL, Zhang TJ, Li S, Mohamed O K, Xue WH, Qian XH, Meng FH. Li XY, et al. Among authors: li s. J Adv Res. 2020 Jul 25;26:95-110. doi: 10.1016/j.jare.2020.07.008. eCollection 2020 Nov. J Adv Res. 2020. PMID: 33133686 Free PMC article.

7

Discovery of novel thymidylate synthase (TS) inhibitors that influence cancer angiogenesis and metabolic reprogramming in NSCLC cells.

Dong G, Li YH, Guo JS, Lin QQ, Deng MY, Xue WH, Li XY, Meng FH. Dong G, et al. Among authors: li yh, li xy. Eur J Med Chem. 2023 Oct 5;258:115600. doi: 10.1016/j.ejmech.2023.115600. Epub 2023 Jun 29. Eur J Med Chem. 2023. PMID: 37437348

8

Novel 4,5-dihydrospiro[benzo[c]azepine-1,1'-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation.

Li S, Li XY, Zhang TJ, Zhu J, Liu KL, Wang DP, Meng FH. Li S, et al. Among authors: li xy. Bioorg Chem. 2021 Jun;111:104840. doi: 10.1016/j.bioorg.2021.104840. Epub 2021 Mar 22. Bioorg Chem. 2021. PMID: 33780687

9

Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis.

Li XY, Wang DP, Li S, Xue WH, Qian XH, Liu KL, Li YH, Lin QQ, Dong G, Meng FH, Jian LY. Li XY, et al. Among authors: li yh, li s. Bioorg Chem. 2022 Feb;119:105469. doi: 10.1016/j.bioorg.2021.105469. Epub 2021 Nov 6. Bioorg Chem. 2022. PMID: 34915285

10

Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.

Lu GQ, Li XY, Mohamed O K, Wang D, Meng FH. Lu GQ, et al. Among authors: li xy. Eur J Med Chem. 2019 Jun 1;171:282-296. doi: 10.1016/j.ejmech.2019.03.047. Epub 2019 Mar 24. Eur J Med Chem. 2019. PMID: 30927565

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