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Page 1
Stereochemistry in the disorder-order continuum of protein interactions.
Newcombe EA, Due AD, Sottini A, Elkjær S, Theisen FF, Fernandes CB, Staby L, Delaforge E, Bartling CRO, Brakti I, Bugge K, Schuler B, Skriver K, Olsen JG, Kragelund BB. Newcombe EA, et al. Among authors: bartling cro. Nature. 2024 Dec;636(8043):762-768. doi: 10.1038/s41586-024-08271-6. Epub 2024 Nov 27. Nature. 2024. PMID: 39604735 Free PMC article.
Targeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation.
Bartling CRO, Jensen TMT, Henry SM, Colliander AL, Sereikaite V, Wenzler M, Jain P, Maric HM, Harpsøe K, Pedersen SW, Clemmensen LS, Haugaard-Kedström LM, Gloriam DE, Ho A, Strømgaard K. Bartling CRO, et al. J Am Chem Soc. 2021 Jan 20;143(2):891-901. doi: 10.1021/jacs.0c10696. Epub 2021 Jan 5. J Am Chem Soc. 2021. PMID: 33398998 Free PMC article.
Probing Backbone Hydrogen Bonds in Proteins by Amide-to-Ester Mutations.
Sereikaitė V, Jensen TMT, Bartling CRO, Jemth P, Pless SA, Strømgaard K. Sereikaitė V, et al. Among authors: bartling cro. Chembiochem. 2018 Oct 18;19(20):2136-2145. doi: 10.1002/cbic.201800350. Epub 2018 Oct 1. Chembiochem. 2018. PMID: 30073762 Review.
Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase.
Bolding JE, Martín-Gago P, Rajabi N, Gamon LF, Hansen TN, Bartling CRO, Strømgaard K, Davies MJ, Olsen CA. Bolding JE, et al. Among authors: bartling cro. Angew Chem Int Ed Engl. 2022 Nov 21;61(47):e202204565. doi: 10.1002/anie.202204565. Epub 2022 Oct 21. Angew Chem Int Ed Engl. 2022. PMID: 36130196 Free PMC article.
Tight control of the APP-Mint1 interaction in regulating amyloid production.
Henry SM, Kistler SA, Lagani GD, Bartling CRO, Özcelik D, Sereikaite V, Strømgaard K, Beffert U, Ho A. Henry SM, et al. Among authors: bartling cro. Brain Res. 2023 Oct 15;1817:148496. doi: 10.1016/j.brainres.2023.148496. Epub 2023 Jul 25. Brain Res. 2023. PMID: 37499733 Free PMC article.
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain.
Christensen NR, De Luca M, Lever MB, Richner M, Hansen AB, Noes-Holt G, Jensen KL, Rathje M, Jensen DB, Erlendsson S, Bartling CR, Ammendrup-Johnsen I, Pedersen SE, Schönauer M, Nissen KB, Midtgaard SR, Teilum K, Arleth L, Sørensen AT, Bach A, Strømgaard K, Meehan CF, Vaegter CB, Gether U, Madsen KL. Christensen NR, et al. EMBO Mol Med. 2020 Jun 8;12(6):e11248. doi: 10.15252/emmm.201911248. Epub 2020 Apr 30. EMBO Mol Med. 2020. PMID: 32352640 Free PMC article.
Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation.
Nielsen AL, Bognar Z, Mothukuri GK, Zarda A, Schüttel M, Merz ML, Ji X, Will EJ, Chinellato M, Bartling CRO, Strømgaard K, Cendron L, Angelini A, Heinis C. Nielsen AL, et al. Among authors: bartling cro. Angew Chem Int Ed Engl. 2024 Jun 21;63(26):e202400350. doi: 10.1002/anie.202400350. Epub 2024 May 24. Angew Chem Int Ed Engl. 2024. PMID: 38602024
14 results