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CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning.
Teter OM, McQuade A, Hagan V, Liang W, Dräger NM, Sattler SM, Holmes BB, Castillo VC, Papakis V, Leng K, Boggess S, Nowakowski TJ, Wells J, Kampmann M. Teter OM, et al. Among authors: wells j. bioRxiv [Preprint]. 2024 Nov 17:2024.06.01.596962. doi: 10.1101/2024.06.01.596962. bioRxiv. 2024. PMID: 39605704 Free PMC article. Preprint.
Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohn's Disease.
Jurickova I, Dreskin BW, Angerman E, Bonkowski E, Tominaga K, Iwasawa K, Braun T, Takebe T, Helmrath MA, Haberman Y, Wells JM, Denson LA. Jurickova I, et al. bioRxiv [Preprint]. 2024 Jan 30:2024.01.30.577959. doi: 10.1101/2024.01.30.577959. bioRxiv. 2024. Update in: J Crohns Colitis. 2024 Aug 30:jjae139. doi: 10.1093/ecco-jcc/jjae139 PMID: 38352573 Free PMC article. Updated. Preprint.
Spatial transcriptomic profiling of coronary endothelial cells in SARS-CoV-2 myocarditis.
Margaroli C, Benson P, Gastanadui MG, Song C, Viera L, Xing D, Wells JM, Patel R, Gaggar A, Payne GA. Margaroli C, et al. Among authors: wells jm. bioRxiv [Preprint]. 2022 Sep 26:2022.09.25.509426. doi: 10.1101/2022.09.25.509426. bioRxiv. 2022. Update in: Front Med (Lausanne). 2023 Mar 09;10:1118024. doi: 10.3389/fmed.2023.1118024 PMID: 36203548 Free PMC article. Updated. Preprint.
Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells.
Rezvani M, Lewis K, Quach S, Iwasawa K, Weihs J, Reza H, Cai Y, Kimura M, Zhang R, Milton Y, Chaturvedi P, Thorner K, Nayak RC, Munera JO, Kramer P, Davis B, Balamurugan A, Ait Ahmed Y, Finke M, Behncke RY, Guillot A, Haegerling R, Polansky J, Bufler P, Cancelas J, Wells J, Yoshimoto M, Takebe T. Rezvani M, et al. Among authors: wells j. bioRxiv [Preprint]. 2024 Oct 12:2024.10.11.617794. doi: 10.1101/2024.10.11.617794. bioRxiv. 2024. PMID: 39416072 Free PMC article. Preprint.
Compressive electron backscatter diffraction imaging.
Broad Z, Robinson AW, Wells J, Nicholls D, Moshtaghpour A, Kirkland AI, Browning ND. Broad Z, et al. Among authors: wells j. J Microsc. 2025 Jan 11. doi: 10.1111/jmi.13379. Online ahead of print. J Microsc. 2025. PMID: 39797608
Mechanism-guided engineering of a minimal biological particle for genome editing.
Ngo W, Peukes J, Baldwin A, Xue ZW, Hwang S, Stickels RR, Lin Z, Satpathy AT, Wells JA, Schekman R, Nogales E, Doudna JA. Ngo W, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2413519121. doi: 10.1073/pnas.2413519121. Epub 2024 Dec 30. Proc Natl Acad Sci U S A. 2025. PMID: 39793042
Ultrasensitive detection of intact SARS-CoV-2 particles in complex biofluids using microfluidic affinity capture.
Rabe DC, Choudhury A, Lee D, Luciani EG, Ho UK, Clark AE, Glasgow JE, Veiga S, Michaud WA, Capen D, Flynn EA, Hartmann N, Garretson AF, Muzikansky A, Goldberg MB, Kwon DS, Yu X, Carlin AF, Theriault Y, Wells JA, Lennerz JK, Lai PS, Rabi SA, Hoang AN, Boland GM, Stott SL. Rabe DC, et al. Among authors: wells ja. Sci Adv. 2025 Jan 10;11(2):eadh1167. doi: 10.1126/sciadv.adh1167. Epub 2025 Jan 10. Sci Adv. 2025. PMID: 39792670 Free PMC article.
Utility of Candidate Genes From an Algorithm Designed to Predict Genetic Risk for Opioid Use Disorder.
Davis CN, Jinwala Z, Hatoum AS, Toikumo S, Agrawal A, Rentsch CT, Edenberg HJ, Baurley JW, Hartwell EE, Crist RC, Gray JC, Justice AC, Gelernter J, Kember RL, Kranzler HR; VA Million Veteran Program. Davis CN, et al. JAMA Netw Open. 2025 Jan 2;8(1):e2453913. doi: 10.1001/jamanetworkopen.2024.53913. JAMA Netw Open. 2025. PMID: 39786773 Free PMC article.
4,437 results