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Page 1
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance.
Baghdadi MB, Houtekamer RM, Perrin L, Rao-Bhatia A, Whelen M, Decker L, Bergert M, Pérez-Gonzàlez C, Bouras R, Gropplero G, Loe AKH, Afkhami-Poostchi A, Chen X, Huang X, Descroix S, Wrana JL, Diz-Muñoz A, Gloerich M, Ayyaz A, Matic Vignjevic D, Kim TH. Baghdadi MB, et al. Among authors: gloerich m. Science. 2024 Nov 29;386(6725):eadj7615. doi: 10.1126/science.adj7615. Epub 2024 Nov 29. Science. 2024. PMID: 39607940
A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion.
Khalil AA, Smits D, Haughton PD, Koorman T, Jansen KA, Verhagen MP, van der Net M, van Zwieten K, Enserink L, Jansen L, El-Gammal AG, Visser D, Pasolli M, Tak M, Westland D, van Diest PJ, Moelans CB, Roukens MG, Tavares S, Fortier AM, Park M, Fodde R, Gloerich M, Zwartkruis FJT, Derksen PW, de Rooij J. Khalil AA, et al. Among authors: gloerich m. Nat Commun. 2024 Jun 7;15(1):4866. doi: 10.1038/s41467-024-49230-z. Nat Commun. 2024. PMID: 38849373 Free PMC article.
Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer.
Strating E, Verhagen MP, Wensink E, Dünnebach E, Wijler L, Aranguren I, De la Cruz AS, Peters NA, Hageman JH, van der Net MMC, van Schelven S, Laoukili J, Fodde R, Roodhart J, Nierkens S, Snippert H, Gloerich M, Rinkes IB, Elias SG, Kranenburg O. Strating E, et al. Among authors: gloerich m. Front Immunol. 2023 May 16;14:1053920. doi: 10.3389/fimmu.2023.1053920. eCollection 2023. Front Immunol. 2023. PMID: 37261365 Free PMC article.
Mechanical forces directing intestinal form and function.
Houtekamer RM, van der Net MC, Maurice MM, Gloerich M. Houtekamer RM, et al. Among authors: gloerich m. Curr Biol. 2022 Jul 25;32(14):R791-R805. doi: 10.1016/j.cub.2022.05.041. Curr Biol. 2022. PMID: 35882203 Free article. Review.
Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.
Heinz MC, Peters NA, Oost KC, Lindeboom RGH, van Voorthuijsen L, Fumagalli A, van der Net MC, de Medeiros G, Hageman JH, Verlaan-Klink I, Borel Rinkes IHM, Liberali P, Gloerich M, van Rheenen J, Vermeulen M, Kranenburg O, Snippert HJG. Heinz MC, et al. Among authors: gloerich m. Cancer Res. 2022 May 16;82(10):1953-1968. doi: 10.1158/0008-5472.CAN-21-0933. Cancer Res. 2022. PMID: 35570706 Free PMC article.
Inside-out regulation of E-cadherin conformation and adhesion.
Koirala R, Priest AV, Yen CF, Cheah JS, Pannekoek WJ, Gloerich M, Yamada S, Sivasankar S. Koirala R, et al. Among authors: gloerich m. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2104090118. doi: 10.1073/pnas.2104090118. Proc Natl Acad Sci U S A. 2021. PMID: 34301871 Free PMC article.
Decoding mechanical cues by molecular mechanotransduction.
Swaminathan V, Gloerich M. Swaminathan V, et al. Among authors: gloerich m. Curr Opin Cell Biol. 2021 Oct;72:72-80. doi: 10.1016/j.ceb.2021.05.006. Epub 2021 Jul 2. Curr Opin Cell Biol. 2021. PMID: 34218181 Free article. Review.
27 results