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Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis.
MacDonald L, Elmesmari A, Somma D, Frew J, Di Mario C, Madhu R, Paoletti A, Simakou T, Hardy OM, Tolusso B, Campobasso D, Perniola S, Gessi M, Gigante MR, Petricca L, Bruno D, Coletto LA, Benvenuto R, Isaacs JD, Filby A, McDonald D, Sim JPX, Jamieson N, Wei K, D'Agostino MA, Millar NL, Milling S, McSharry C, Gremese E, Affleck K, Baker KF, McInnes IB, Otto TD, Korsunsky I, Alivernini S, Kurowska-Stolarska M. MacDonald L, et al. Among authors: somma d. Immunity. 2024 Dec 10;57(12):2843-2862.e12. doi: 10.1016/j.immuni.2024.11.004. Epub 2024 Nov 27. Immunity. 2024. PMID: 39609125 Free article.
Pediatric-onset Multiple Sclerosis treatment: a multicentre observational study comparing natalizumab with fingolimod.
Carotenuto A, Di Monaco C, Papetti L, Borriello G, Signoriello E, Masciulli C, Tomassini V, De Luca G, Ianniello A, Lus G, Novarella F, Spiezia AL, Di Somma D, Moccia M, Petracca M, Iacovazzo C, Servillo G, Portaccio E, Triassi M, Amato MP, Pozzilli C, Valeriani M, Brescia Morra V, Lanzillo R. Carotenuto A, et al. Among authors: di somma d. J Neurol. 2024 Oct;271(10):6773-6781. doi: 10.1007/s00415-024-12610-y. Epub 2024 Aug 23. J Neurol. 2024. PMID: 39177751 Free PMC article.
miR-155-overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T-cell activation.
Olsson AM, Povoleri GAM, Somma D, Ridley ML, Rizou T, Lalnunhlimi S, Macdonald L, Rajasekhar M, Martinez-Nunez RT, Kurowska-Stolarska M, Taams LS. Olsson AM, et al. Among authors: somma d. Clin Exp Immunol. 2022 Apr 4;207(2):188-198. doi: 10.1093/cei/uxab016. Clin Exp Immunol. 2022. PMID: 35020867 Free PMC article.
COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes.
MacDonald L, Alivernini S, Tolusso B, Elmesmari A, Somma D, Perniola S, Paglionico A, Petricca L, Bosello SL, Carfì A, Sali M, Stigliano E, Cingolani A, Murri R, Arena V, Fantoni M, Antonelli M, Landi F, Franceschi F, Sanguinetti M, McInnes IB, McSharry C, Gasbarrini A, Otto TD, Kurowska-Stolarska M, Gremese E. MacDonald L, et al. Among authors: somma d. JCI Insight. 2021 Jun 18;6(13):e147413. doi: 10.1172/jci.insight.147413. JCI Insight. 2021. PMID: 34143756 Free PMC article.
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis.
Alivernini S, MacDonald L, Elmesmari A, Finlay S, Tolusso B, Gigante MR, Petricca L, Di Mario C, Bui L, Perniola S, Attar M, Gessi M, Fedele AL, Chilaka S, Somma D, Sansom SN, Filer A, McSharry C, Millar NL, Kirschner K, Nerviani A, Lewis MJ, Pitzalis C, Clark AR, Ferraccioli G, Udalova I, Buckley CD, Gremese E, McInnes IB, Otto TD, Kurowska-Stolarska M. Alivernini S, et al. Among authors: somma d. Nat Med. 2020 Aug;26(8):1295-1306. doi: 10.1038/s41591-020-0939-8. Epub 2020 Jun 29. Nat Med. 2020. PMID: 32601335 Free article.
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