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CRISPR-Cas9-mediated genome editing delivered by a single AAV9 vector inhibits HSV-1 reactivation in a latent rabbit keratitis model.
Amrani N, Luk K, Singh P, Shipley M, Isik M, Donadoni M, Bellizzi A, Khalili K, Sariyer IK, Neumann D, Gordon J, Ruan GX. Amrani N, et al. Among authors: gordon j. Mol Ther Methods Clin Dev. 2024 Aug 14;32(3):101303. doi: 10.1016/j.omtm.2024.101303. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39610766 Free PMC article.
CRISPR based editing of SIV proviral DNA in ART treated non-human primates.
Mancuso P, Chen C, Kaminski R, Gordon J, Liao S, Robinson JA, Smith MD, Liu H, Sariyer IK, Sariyer R, Peterson TA, Donadoni M, Williams JB, Siddiqui S, Bunnell BA, Ling B, MacLean AG, Burdo TH, Khalili K. Mancuso P, et al. Among authors: gordon j. Nat Commun. 2020 Nov 27;11(1):6065. doi: 10.1038/s41467-020-19821-7. Nat Commun. 2020. PMID: 33247091 Free PMC article.
Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.
Burdo TH, Chen C, Kaminski R, Sariyer IK, Mancuso P, Donadoni M, Smith MD, Sariyer R, Caocci M, Liao S, Liu H, Huo W, Zhao H, Misamore J, Lewis MG, Simonyan V, Thompson EE, Xu EY, Cradick TJ, Gordon J, Khalili K. Burdo TH, et al. Among authors: gordon j. Gene Ther. 2024 May;31(5-6):224-233. doi: 10.1038/s41434-023-00410-4. Epub 2023 Aug 17. Gene Ther. 2024. PMID: 37587230 Free PMC article.
Correction: Preclinical safety and biodistribution of CRISPR targeting SIV in non-human primates.
Burdo TH, Chen C, Kaminski R, Sariyer IK, Mancuso P, Donadoni M, Smith MD, Sariyer R, Caocci M, Liao S, Liu H, Huo W, Zhao H, Misamore J, Lewis MG, Simonyan V, Thompson EE, Xu EY, Cradick TJ, Gordon J, Khalili K. Burdo TH, et al. Among authors: gordon j. Gene Ther. 2024 Jul;31(7-8):434-435. doi: 10.1038/s41434-023-00438-6. Gene Ther. 2024. PMID: 38212405 Free PMC article. No abstract available.
Suppression of Zika Virus Infection in the Brain by the Antiretroviral Drug Rilpivirine.
Sariyer IK, Gordon J, Burdo TH, Wollebo HS, Gianti E, Donadoni M, Bellizzi A, Cicalese S, Loomis R, Robinson JA, Carnevale V, Steiner J, Ozdener MH, Miller AD, Amini S, Klein ML, Khalili K. Sariyer IK, et al. Among authors: gordon j. Mol Ther. 2019 Dec 4;27(12):2067-2079. doi: 10.1016/j.ymthe.2019.10.006. Epub 2019 Oct 11. Mol Ther. 2019. PMID: 31653397 Free PMC article.
Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice.
Dash PK, Kaminski R, Bella R, Su H, Mathews S, Ahooyi TM, Chen C, Mancuso P, Sariyer R, Ferrante P, Donadoni M, Robinson JA, Sillman B, Lin Z, Hilaire JR, Banoub M, Elango M, Gautam N, Mosley RL, Poluektova LY, McMillan J, Bade AN, Gorantla S, Sariyer IK, Burdo TH, Young WB, Amini S, Gordon J, Jacobson JM, Edagwa B, Khalili K, Gendelman HE. Dash PK, et al. Among authors: gordon j. Nat Commun. 2019 Jul 2;10(1):2753. doi: 10.1038/s41467-019-10366-y. Nat Commun. 2019. PMID: 31266936 Free PMC article.
Strategic self-limiting production of infectious HIV particles by CRISPR in permissive cells.
Liu H, Chen C, Liao S, Sohaii DK, Cruz CRY, Burdo TH, Cradick TJ, Mehta A, Barrero C, Florez M, Gordon J, Grauzam S, Dressman J, Amini S, Bollard CM, Kaminski R, Khalili K. Liu H, et al. Among authors: gordon j. Mol Ther Nucleic Acids. 2023 May 19;32:1010-1025. doi: 10.1016/j.omtn.2023.04.027. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37346975 Free PMC article.
4,973 results