Sun SL - Search Results

1

Kinase-Bench: Comprehensive Benchmarking Tools and Guidance for Achieving Selectivity in Kinase Drug Discovery.

Wei TH, Zhou SS, Jing XL, Liu JC, Sun M, Zhao ZH, Li QQ, Wang ZX, Yang J, Zhou Y, Wang X, Ling CX, Ding N, Xue X, Yu YC, Wang XL, Yin XY, Sun SL, Cao P, Li NG, Shi ZH. Wei TH, et al. Among authors: sun sl. J Chem Inf Model. 2024 Dec 23;64(24):9528-9550. doi: 10.1021/acs.jcim.4c01830. Epub 2024 Dec 2. J Chem Inf Model. 2024. PMID: 39623285

2

Small-Molecule Fms-like Tyrosine Kinase 3 Inhibitors: An Attractive and Efficient Method for the Treatment of Acute Myeloid Leukemia.

Zhong Y, Qiu RZ, Sun SL, Zhao C, Fan TY, Chen M, Li NG, Shi ZH. Zhong Y, et al. Among authors: sun sl. J Med Chem. 2020 Nov 12;63(21):12403-12428. doi: 10.1021/acs.jmedchem.0c00696. Epub 2020 Jul 21. J Med Chem. 2020. PMID: 32659083 Review.

3

Bufotenine and its derivatives: synthesis, analgesic effects identification and computational target prediction.

Zhao C, Chen M, Sun SL, Wang JJ, Zhong Y, Chen HH, Li HM, Xu H, Li NG, Ma HY, Wang XL. Zhao C, et al. Among authors: sun sl. Chin J Nat Med. 2021 Jun;19(6):454-463. doi: 10.1016/S1875-5364(21)60044-4. Chin J Nat Med. 2021. PMID: 34092296

4

An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.

Xue X, Kang JB, Yang X, Li N, Chang L, Ji J, Meng XK, Zhang HQ, Zhong Y, Yu SP, Wu WY, Wang XL, Li NG, Sun SL. Xue X, et al. Among authors: sun sl. Eur J Med Chem. 2022 Jan 5;227:113871. doi: 10.1016/j.ejmech.2021.113871. Epub 2021 Sep 28. Eur J Med Chem. 2022. PMID: 34638033

5

AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma.

Gu C, Wang Y, Zhang L, Qiao L, Sun S, Shao M, Tang X, Ding P, Tang C, Cao Y, Zhou Y, Guo M, Wei R, Li N, Xiao Y, Duan J, Yang Y. Gu C, et al. J Exp Clin Cancer Res. 2022 Jan 6;41(1):11. doi: 10.1186/s13046-021-02220-1. J Exp Clin Cancer Res. 2022. PMID: 34991674 Free PMC article.

6

Medicinal Chemistry Strategies for the Development of Bruton's Tyrosine Kinase Inhibitors against Resistance.

Sun SL, Wu SH, Kang JB, Ma YY, Chen L, Cao P, Chang L, Ding N, Xue X, Li NG, Shi ZH. Sun SL, et al. J Med Chem. 2022 Jun 9;65(11):7415-7437. doi: 10.1021/acs.jmedchem.2c00030. Epub 2022 May 20. J Med Chem. 2022. PMID: 35594541 Review.

7

Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.

Kang JB, Chen L, Leng XJ, Wang JJ, Cheng Y, Wu SH, Ma YY, Yang LJ, Cao YH, Yang X, Tong ZJ, Wu JZ, Wang YB, Zhou H, Liu JC, Ding N, Dai WC, Yu YC, Xue X, Sun SL, Dai XB, Chang L, Wang XL, Li NG, Shi ZH. Kang JB, et al. Among authors: sun sl. Bioorg Med Chem. 2022 Sep 15;70:116937. doi: 10.1016/j.bmc.2022.116937. Epub 2022 Jul 16. Bioorg Med Chem. 2022. PMID: 35863236

8

Discovery of 4-(4-aminophenyl)-6-phenylisoxazolo[3,4-b]pyridine-3-amine derivatives as novel FLT3 covalent inhibitors for the intervention of acute myeloid leukemia.

Wang QX, Wang YB, Sha JK, Zhou H, Liu JC, Wu JZ, Tong ZJ, Cai J, Chen ZJ, Zhang CQ, Zheng XR, Wang JJ, Wang XL, Xue X, Yu YC, Ding N, Leng XJ, Dai WC, Sun SL, Chang L, Li NG, Shi ZH. Wang QX, et al. Among authors: sun sl. Drug Dev Res. 2023 Apr;84(2):296-311. doi: 10.1002/ddr.22032. Epub 2023 Jan 16. Drug Dev Res. 2023. PMID: 36644989

9

Design and synthesis of selective FLT3 inhibitors via exploration of back pocket II.

Wang QX, Cao YH, Yang LJ, Ma YY, Li N, Wu SH, Chen L, Wu JZ, Tong ZJ, Wang XL, Xue X, Ding N, Leng XJ, Chang L, Dai WC, Yu YC, Sun SL, Yang Y, Li NG, Shi ZH. Wang QX, et al. Among authors: sun sl. Future Med Chem. 2023 Jan;15(1):57-71. doi: 10.4155/fmc-2022-0231. Epub 2023 Jan 18. Future Med Chem. 2023. PMID: 36651264

10

Challenges for the development of mutant isocitrate dehydrogenases 1 inhibitors to treat glioma.

Wang QX, Zhang PY, Li QQ, Tong ZJ, Wu JZ, Yu SP, Yu YC, Ding N, Leng XJ, Chang L, Xu JG, Sun SL, Yang Y, Li NG, Shi ZH. Wang QX, et al. Among authors: sun sl. Eur J Med Chem. 2023 Sep 5;257:115464. doi: 10.1016/j.ejmech.2023.115464. Epub 2023 May 12. Eur J Med Chem. 2023. PMID: 37235998 Review.

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