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Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia.
Sun SL, Wu JZ, Wang JJ, Zhou H, Zhang CQ, Tong ZJ, Wang YB, Sha JK, Wang QX, Liu JC, Zheng XR, Li QQ, Zhang MY, Yang J, Wei TH, Wang ZX, Yu YC, Ding N, Leng XJ, Xue X, Li HM, Dai WC, Yin XY, Yang Y, Duan JA, Li NG, Shi ZH. Sun SL, et al. Among authors: wang zx, wang jj, wang qx, wang yb. Biomed Pharmacother. 2023 Dec 31;169:115905. doi: 10.1016/j.biopha.2023.115905. Epub 2023 Nov 24. Biomed Pharmacother. 2023. PMID: 38000356 Free article.
Correction to "Discovery of RORγ Allosteric Fluorescent Probes and Their Application: Fluorescence Polarization, Screening, and Bioimaging".
Yu YC, Tong ZJ, Liang XT, Wu JZ, Xu YJ, Wang JJ, Zhang MY, Wei TH, Yang J, Wang YB, Wang QX, Li QQ, Wang ZX, Leng XJ, Ding N, Xue X, Sun SL, Li NG, Wang XL. Yu YC, et al. Among authors: wang zx, wang jj, wang xl, wang qx, wang yb. J Med Chem. 2024 Apr 11;67(7):5960-5961. doi: 10.1021/acs.jmedchem.4c00606. Epub 2024 Mar 26. J Med Chem. 2024. PMID: 38530955 No abstract available.
Exploring drug repositioning possibilities of kinase inhibitors via molecular simulation.
Wang QX, Cai J, Chen ZJ, Liu JC, Wang JJ, Zhou H, Li QQ, Wang ZX, Wang YB, Tong ZJ, Yang J, Wei TH, Zhang MY, Zhou Y, Dai WC, Ding N, Leng XJ, Yin XY, Sun SL, Yu YC, Li NG, Shi ZH. Wang QX, et al. Among authors: wang zx, wang jj, wang yb. Mol Inform. 2024 Sep;43(9):e202300336. doi: 10.1002/minf.202300336. Epub 2024 Jun 21. Mol Inform. 2024. PMID: 39031899
Discovery of SILA-123 as a Highly Potent FLT3 Inhibitor for the Treatment of Acute Myeloid Leukemia with Various FLT3 Mutations.
Wei TH, Wang ZX, Lu MY, Xu YJ, Yang J, Ni XF, Cheng Y, Zhang MY, Liu JC, Li QQ, Cai J, Chen ZJ, Kang JB, Li N, Dai WC, Ding N, Yu YC, Leng XJ, Xue X, Wang XL, Sun SL, Yang Y, Li NG, Shi ZH. Wei TH, et al. Among authors: wang zx, wang xl. J Med Chem. 2024 Dec 26;67(24):21752-21780. doi: 10.1021/acs.jmedchem.4c00529. Epub 2024 Sep 11. J Med Chem. 2024. PMID: 39258312
Discovery of 1-(Phenylsulfonyl)-1,2,3,4-tetrahydroquinoline Derivative as Orally Bioavailable and Safe RORγt Inverse Agonists for Potential Treatment of Rheumatoid Arthritis.
Sun SL, Xu HJ, Jiang XL, Zhou J, Shi W, Wang XJ, Song W, Chang XY, Ma XQ, Zou XF, Wu SH, Yang J, Li QQ, Wang ZX, Cai J, Yu SP, Wang QX, Wei TH, Wu JZ, Tong ZJ, Zhou Y, Wang YB, Yu YC, Leng XJ, Ding N, Shi ZH, Dai WC, Xue X, Li NG, Wang XL. Sun SL, et al. Among authors: wang zx, wang xj, wang xl, wang qx, wang yb. J Med Chem. 2024 Nov 28;67(22):20315-20342. doi: 10.1021/acs.jmedchem.4c01727. Epub 2024 Nov 15. J Med Chem. 2024. PMID: 39546350
1,938 results