Deep mutational scanning of CYP2C19 in human cells reveals a substrate specificity-abundance tradeoff.
Boyle GE, Sitko KA, Galloway JG, Haddox HK, Bianchi AH, Dixon A, Wheelock MK, Vandi AJ, Wang ZR, Thomson RES, Garge RK, Rettie AE, Rubin AF, Geck RC, Gillam EMJ, DeWitt WS, Matsen FA 4th, Fowler DM.
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Genetics. 2024 Nov 6;228(3):iyae156. doi: 10.1093/genetics/iyae156.
Genetics. 2024.
PMID: 39319420