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Page 1
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist.
Polex-Wolf J, Deibler K, Hogendorf WFJ, Bau S, Glendorf T, Stidsen CE, Tornøe CW, Tiantang D, Lundh S, Pyke C, Tomlinson AJ, Kernodle S, Magrisso IJ, Conde-Frieboes KW, Myers MG Jr, Knudsen LB, Seeley RJ. Polex-Wolf J, et al. Among authors: pyke c. Sci Transl Med. 2024 Dec 4;16(776):eadk4908. doi: 10.1126/scitranslmed.adk4908. Epub 2024 Dec 4. Sci Transl Med. 2024. PMID: 39630884
Semaglutide lowers body weight in rodents via distributed neural pathways.
Gabery S, Salinas CG, Paulsen SJ, Ahnfelt-Rønne J, Alanentalo T, Baquero AF, Buckley ST, Farkas E, Fekete C, Frederiksen KS, Helms HCC, Jeppesen JF, John LM, Pyke C, Nøhr J, Lu TT, Polex-Wolf J, Prevot V, Raun K, Simonsen L, Sun G, Szilvásy-Szabó A, Willenbrock H, Secher A, Knudsen LB, Hogendorf WFJ. Gabery S, et al. Among authors: pyke c. JCI Insight. 2020 Mar 26;5(6):e133429. doi: 10.1172/jci.insight.133429. JCI Insight. 2020. PMID: 32213703 Free PMC article.
A genetic map of the mouse dorsal vagal complex and its role in obesity.
Ludwig MQ, Cheng W, Gordian D, Lee J, Paulsen SJ, Hansen SN, Egerod KL, Barkholt P, Rhodes CJ, Secher A, Knudsen LB, Pyke C, Myers MG Jr, Pers TH. Ludwig MQ, et al. Among authors: pyke c. Nat Metab. 2021 Apr;3(4):530-545. doi: 10.1038/s42255-021-00363-1. Epub 2021 Mar 25. Nat Metab. 2021. PMID: 33767443
Glucagon-like peptide-1 receptor expression in the human eye.
Hebsgaard JB, Pyke C, Yildirim E, Knudsen LB, Heegaard S, Kvist PH. Hebsgaard JB, et al. Among authors: pyke c. Diabetes Obes Metab. 2018 Sep;20(9):2304-2308. doi: 10.1111/dom.13339. Epub 2018 May 24. Diabetes Obes Metab. 2018. PMID: 29707863 Free PMC article.
Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist.
Buckley ST, Bækdal TA, Vegge A, Maarbjerg SJ, Pyke C, Ahnfelt-Rønne J, Madsen KG, Schéele SG, Alanentalo T, Kirk RK, Pedersen BL, Skyggebjerg RB, Benie AJ, Strauss HM, Wahlund PO, Bjerregaard S, Farkas E, Fekete C, Søndergaard FL, Borregaard J, Hartoft-Nielsen ML, Knudsen LB. Buckley ST, et al. Among authors: pyke c. Sci Transl Med. 2018 Nov 14;10(467):eaar7047. doi: 10.1126/scitranslmed.aar7047. Sci Transl Med. 2018. PMID: 30429357 Clinical Trial.
161 results