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Acid ceramidase controls proteasome inhibitor resistance and is a novel therapeutic target for the treatment of relapsed / refractory multiple myeloma.
Bishop RT, Li T, Sudalagunta P, Nasr M, Nyman KJ, Alugubelli RR, Meads M, Frieling J, Nerlakanti N, Tauro M, Fang B, Grant S, Koomen J, Silva AS, Shain KH, Lynch CC. Bishop RT, et al. Among authors: fang b. Haematologica. 2024 Dec 5. doi: 10.3324/haematol.2024.285587. Online ahead of print. Haematologica. 2024. PMID: 39633543 Free article.
Proteometabolomics of Melphalan Resistance in Multiple Myeloma.
Koomen DC, Guingab-Cagmat JD, Oliveira PS, Fang B, Liu M, Welsh EA, Meads MB, Nguyen T, Meke L, Eschrich SA, Shain KH, Garrett TJ, Koomen JM. Koomen DC, et al. Among authors: fang b. Methods Mol Biol. 2019;1996:273-296. doi: 10.1007/978-1-4939-9488-5_21. Methods Mol Biol. 2019. PMID: 31127562 Free PMC article.
Metabolic Changes Are Associated with Melphalan Resistance in Multiple Myeloma.
Koomen DC, Meads MB, Magaletti DM, Guingab-Cagmat JD, Oliveira PS, Fang B, Liu M, Welsh EA, Meke LE, Jiang Z, Hampton OA, Tungesvik A, De Avila G, Alugubelli RR, Nishihori T, Silva AS, Eschrich SA, Garrett TJ, Koomen JM, Shain KH. Koomen DC, et al. Among authors: fang b. J Proteome Res. 2021 Jun 4;20(6):3134-3149. doi: 10.1021/acs.jproteome.1c00022. Epub 2021 May 20. J Proteome Res. 2021. PMID: 34014671 Free PMC article.
Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma.
Mostofa A, Distler A, Meads MB, Sahakian E, Powers JJ, Achille A, Noyes D, Wright G, Fang B, Izumi V, Koomen J, Rampakrishnan R, Nguyen TP, De Avila G, Silva AS, Sudalagunta P, Canevarolo RR, Siqueira Silva MDC, Alugubelli RR, Dai HA, Kulkarni A, Dalton WS, Hampton OA, Welsh EA, Teer JK, Tungesvik A, Wright KL, Pinilla-Ibarz J, Sotomayor EM, Shain KH, Brayer J. Mostofa A, et al. Among authors: fang b. JCI Insight. 2021 Dec 22;6(24):e151713. doi: 10.1172/jci.insight.151713. JCI Insight. 2021. PMID: 34793338 Free PMC article.
Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma.
Meads MB, Fang B, Mathews L, Gemmer J, Nong L, Rosado-Lopez I, Nguyen T, Ring JE, Matsui W, MacLeod AR, Pachter JA, Hazlehurst LA, Koomen JM, Shain KH. Meads MB, et al. Among authors: fang b. Oncogene. 2016 May;35(21):2723-34. doi: 10.1038/onc.2015.334. Epub 2015 Sep 21. Oncogene. 2016. PMID: 26387544 Free PMC article.
PLK1 stabilizes a MYC-dependent kinase network in aggressive B cell lymphomas.
Ren Y, Bi C, Zhao X, Lwin T, Wang C, Yuan J, Silva AS, Shah BD, Fang B, Li T, Koomen JM, Jiang H, Chavez JC, Pham LV, Sudalagunta PR, Wan L, Wang X, Dalton WS, Moscinski LC, Shain KH, Vose J, Cleveland JL, Sotomayor EM, Fu K, Tao J. Ren Y, et al. Among authors: fang b. J Clin Invest. 2018 Dec 3;128(12):5517-5530. doi: 10.1172/JCI122533. Epub 2018 Nov 5. J Clin Invest. 2018. PMID: 30260324 Free PMC article.
Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma.
Zhao X, Lwin T, Silva A, Shah B, Tao J, Fang B, Zhang L, Fu K, Bi C, Li J, Jiang H, Meads MB, Jacobson T, Silva M, Distler A, Darville L, Zhang L, Han Y, Rebatchouk D, Di Liberto M, Moscinski LC, Koomen JM, Dalton WS, Shain KH, Wang M, Sotomayor E, Tao J. Zhao X, et al. Among authors: fang b. Nat Commun. 2017 Apr 18;8:14920. doi: 10.1038/ncomms14920. Nat Commun. 2017. PMID: 28416797 Free PMC article.
2,512 results