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X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes.
Hasenbein TP, Hoelzl S, Smith ZD, Gerhardinger C, Gonner MOC, Aguilar-Pimentel A, Amarie OV, Becker L, Calzada-Wack J, Dragano NRV, da Silva-Buttkus P, Garrett L, Hölter SM, Kraiger M, Östereicher MA, Rathkolb B, Sanz-Moreno A, Spielmann N, Wurst W, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Meissner A, Engelhardt S, Rinn JL, Andergassen D. Hasenbein TP, et al. Among authors: rinn jl. Nat Commun. 2024 Dec 5;15(1):10631. doi: 10.1038/s41467-024-54673-5. Nat Commun. 2024. PMID: 39638999 Free PMC article.
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.
Lewandowski JP, Lee JC, Hwang T, Sunwoo H, Goldstein JM, Groff AF, Chang NP, Mallard W, Williams A, Henao-Meija J, Flavell RA, Lee JT, Gerhardinger C, Wagers AJ, Rinn JL. Lewandowski JP, et al. Among authors: rinn jl. Nat Commun. 2019 Nov 13;10(1):5137. doi: 10.1038/s41467-019-12970-4. Nat Commun. 2019. PMID: 31723143 Free PMC article.
Function and evolution of local repeats in the Firre locus.
Hacisuleyman E, Shukla CJ, Weiner CL, Rinn JL. Hacisuleyman E, et al. Among authors: rinn jl. Nat Commun. 2016 Mar 24;7:11021. doi: 10.1038/ncomms11021. Nat Commun. 2016. PMID: 27009974 Free PMC article.
Genetic determinants and epigenetic effects of pioneer-factor occupancy.
Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A. Donaghey J, et al. Among authors: rinn jl. Nat Genet. 2018 Feb;50(2):250-258. doi: 10.1038/s41588-017-0034-3. Epub 2018 Jan 22. Nat Genet. 2018. PMID: 29358654 Free PMC article.
168 results