Sharma AK - Search Results

1

Discovery of BBO-8520, a first-in-class direct and covalent dual inhibitor of GTP-bound (ON) and GDP-bound (OFF) KRASG12C.

Maciag AE, Stice JP, Wang B, Sharma AK, Chan AH, Lin K, Singh D, Dyba M, Yang Y, Setoodeh S, Smith BP, Ju JH, Jeknic S, Rabara D, Zhang Z, Larsen EK, Esposito D, Denson JP, Ranieri M, Meynardie M, Mehdizadeh S, Alexander PA, Abreu Blanco M, Turner DM, Xu R, Lightstone FC, Wong KK, Stephen AG, Wang K, Simanshu DK, Sinkevicius KW, Nissley DV, Wallace E, McCormick F, Beltran PJ. Maciag AE, et al. Among authors: sharma ak. Cancer Discov. 2024 Dec 6. doi: 10.1158/2159-8290.CD-24-0840. Online ahead of print. Cancer Discov. 2024. PMID: 39642212

2

NMR ¹H, ¹³C, ¹⁵N backbone resonance assignments of the T35S and oncogenic T35S/Q61L mutants of human KRAS4b in the active, GppNHp-bound conformation.

Sharma AK, Dyba M, Tonelli M, Smith B, Gillette WK, Esposito D, Nissley DV, McCormick F, Maciag AE. Sharma AK, et al. Biomol NMR Assign. 2022 Apr;16(1):1-8. doi: 10.1007/s12104-021-10050-7. Epub 2021 Oct 22. Biomol NMR Assign. 2022. PMID: 34686998 Free PMC article.

3

NMR ¹H,¹³C, ¹⁵N backbone and ¹³C side chain resonance assignment of the G12C mutant of human K-Ras bound to GDP.

Sharma AK, Lee SJ, Rigby AC, Townson SA. Sharma AK, et al. Biomol NMR Assign. 2018 Oct;12(2):269-272. doi: 10.1007/s12104-018-9821-8. Epub 2018 May 2. Biomol NMR Assign. 2018. PMID: 29721757 Free PMC article.

4

Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death.

Jo H, Mondal S, Tan D, Nagata E, Takizawa S, Sharma AK, Hou Q, Shanmugasundaram K, Prasad A, Tung JK, Tejeda AO, Man H, Rigby AC, Luo HR. Jo H, et al. Among authors: sharma ak. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10581-6. doi: 10.1073/pnas.1202810109. Epub 2012 Jun 11. Proc Natl Acad Sci U S A. 2012. PMID: 22689977 Free PMC article.

5

Ancillary tests for brain death.

Duvuru S, Sanker V, Mishra RK, Sharma AK, Lim SL, Baskar N, Sharma VK. Duvuru S, et al. Among authors: sharma ak. Front Neurol. 2025 Jan 7;15:1491263. doi: 10.3389/fneur.2024.1491263. eCollection 2024. Front Neurol. 2025. PMID: 39839883 Free PMC article. Review.

6

Emergency carotid endarterectomy with stent retrieval in a patient with stent migration following failed carotid artery stenting.

Meena D, Patel S, Chandolia P, Tiwari S, Mathur A, Sharma AK. Meena D, et al. Among authors: sharma ak. Indian J Thorac Cardiovasc Surg. 2025 Feb;41(2):206-209. doi: 10.1007/s12055-024-01778-7. Epub 2024 Jul 8. Indian J Thorac Cardiovasc Surg. 2025. PMID: 39822863

7

An Acellular Platform to Drive Urinary Bladder Tissue Regeneration.

Kini M, Bury MI, Sharma AK. Kini M, et al. Among authors: sharma ak. Adv Ther (Weinh). 2025 Jan;8(1):2400158. doi: 10.1002/adtp.202400158. Epub 2024 Dec 20. Adv Ther (Weinh). 2025. PMID: 39822772 Free PMC article.

8

Half a Century's Quest for Seasonal Hyperacute Panuveitis (SHAPU): From Academic Curiosity to Public Health Concern.

Goh YY, Sitaula RK, Rojas-Carabali W, Agrawal R, Karki P, Gurung H, Shrestha E, Joshi P, Khatri A, Sharma AK, Joshi SN, Ram Bhusal D, Prasad Upadhyay M. Goh YY, et al. Among authors: sharma ak. Ocul Immunol Inflamm. 2025 Jan 13:1-8. doi: 10.1080/09273948.2024.2444510. Online ahead of print. Ocul Immunol Inflamm. 2025. PMID: 39804087 Review.

9

Role of Low-Cost Negative Pressure Dressing in the Management of Sacral Pressure Injuries and its Impact on Functional Recovery in Neuro-rehabilitation: A Retrospective Case Series.

Sharma AK, Sunaina K, Nongrum IP, Asthana SS. Sharma AK, et al. J Orthop Case Rep. 2025 Jan;15(1):241-246. doi: 10.13107/jocr.2025.v15.i01.5188. J Orthop Case Rep. 2025. PMID: 39801846 Free PMC article.

10

Investigations on segmentation-based fractal texture for texture classification in the presence of Gaussian noise.

Tiwari S, Sharma AK, Abdul Aziz I, Gupta D, Jain A, Mahdin H, Athithan S, Hidayat R. Tiwari S, et al. Among authors: sharma ak. PLoS One. 2025 Jan 10;20(1):e0315135. doi: 10.1371/journal.pone.0315135. eCollection 2025. PLoS One. 2025. PMID: 39792787 Free PMC article.

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