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Page 1
Attribute ranging as a coordinated strategy between drug substance and drug product to accelerate commercial process nomination.
Hartmanshenn C, Bechtold A, Kwok T, Mora J, Contrella N, Confer A, Bade R, Andreani T, Hughes JME, Chen B, Sirota E, Codan L, Lamberto DJ, Xu Y, Salehi N, Crowley S. Hartmanshenn C, et al. Among authors: bade r. J Pharm Sci. 2024 Dec 5:S0022-3549(24)00513-6. doi: 10.1016/j.xphs.2024.11.008. Online ahead of print. J Pharm Sci. 2024. PMID: 39645078
Development of a Robust Manufacturing Route for Molnupiravir, an Antiviral for the Treatment of COVID-19.
Fier PS, Xu Y, Poirier M, Brito G, Zheng M, Bade R, Sirota E, Stone K, Tan L, Humphrey GR, Chang D, Bothe J, Zhang Y, Bernardoni F, Castro S, Zompa MA, Taylor J, Sirk KM, Diaz-Santana A, Diribe I, Emerson KM, Krishnamurthi B, Zhao R, Ward M, Xiao C, Ouyand H, Zhan J, Morris WJ. Fier PS, et al. Among authors: bade r. Org Process Res Dev. 2021 Dec 17;25(12):2806-2815. doi: 10.1021/acs.oprd.1c00400. Epub 2021 Dec 10. Org Process Res Dev. 2021. PMID: 35095257 Review.
Diverse Catalytic Reactions for the Stereoselective Synthesis of Cyclic Dinucleotide MK-1454.
Benkovics T, Peng F, Phillips EM, An C, Bade RS, Chung CK, Dance ZEX, Fier PS, Forstater JH, Liu Z, Liu Z, Maligres PE, Marshall NM, Salehi Marzijarani N, McIntosh JA, Miller SP, Moore JC, Neel AJ, Obligacion JV, Pan W, Pirnot MT, Poirier M, Reibarkh M, Sherry BD, Song ZJ, Tan L, Turnbull BWH, Verma D, Waldman JH, Wang L, Wang T, Winston MS, Xu F. Benkovics T, et al. J Am Chem Soc. 2022 Apr 6;144(13):5855-5863. doi: 10.1021/jacs.1c12106. Epub 2022 Mar 25. J Am Chem Soc. 2022. PMID: 35333525
A kinase-cGAS cascade to synthesize a therapeutic STING activator.
McIntosh JA, Liu Z, Andresen BM, Marzijarani NS, Moore JC, Marshall NM, Borra-Garske M, Obligacion JV, Fier PS, Peng F, Forstater JH, Winston MS, An C, Chang W, Lim J, Huffman MA, Miller SP, Tsay FR, Altman MD, Lesburg CA, Steinhuebel D, Trotter BW, Cumming JN, Northrup A, Bu X, Mann BF, Biba M, Hiraga K, Murphy GS, Kolev JN, Makarewicz A, Pan W, Farasat I, Bade RS, Stone K, Duan D, Alvizo O, Adpressa D, Guetschow E, Hoyt E, Regalado EL, Castro S, Rivera N, Smith JP, Wang F, Crespo A, Verma D, Axnanda S, Dance ZEX, Devine PN, Tschaen D, Canada KA, Bulger PG, Sherry BD, Truppo MD, Ruck RT, Campeau LC, Bennett DJ, Humphrey GR, Campos KR, Maddess ML. McIntosh JA, et al. Among authors: bade rs. Nature. 2022 Mar;603(7901):439-444. doi: 10.1038/s41586-022-04422-9. Epub 2022 Mar 16. Nature. 2022. PMID: 35296845
Paediatric renal hilar paraganglioma.
Bade R, Menon P, Mitra S. Bade R, et al. BMJ Case Rep. 2024 Sep 30;17(9):e262021. doi: 10.1136/bcr-2024-262021. BMJ Case Rep. 2024. PMID: 39349300
Wastewater-based evaluation of the efficacy of oxycodone regulations in Australia.
Verhagen R, Gerber C, Thai PK, Connor J, Loveday B, Bade R, O'Brien J, Jaunay EL, Simpson BS, Chan G, Hall W, Thomas KV, Mueller JF, Tscharke BJ. Verhagen R, et al. Among authors: bade r. Addiction. 2024 Dec;119(12):2153-2161. doi: 10.1111/add.16653. Epub 2024 Sep 11. Addiction. 2024. PMID: 39259037
114 results