Wu J - Search Results

1

Structure-activity relationship study of novel evodiamine amino acid conjugates with potent anti-colorectal cancer efficacy.

Chen S, Zhang X, Mo H, Peng Y, An Z, Wu J, Wei X, Zhang S, Xiong Y, Jiang W, Peng X, Zhuo L, Lei Z, Wang Z, Hu Z. Chen S, et al. Among authors: wu j. Eur J Med Chem. 2025 Feb 5;283:117132. doi: 10.1016/j.ejmech.2024.117132. Epub 2024 Dec 3. Eur J Med Chem. 2025. PMID: 39647421

2

Structure-activity relationship study of 1,6-naphthyridinone derivatives as selective type II AXL inhibitors with potent antitumor efficacy.

Zhuo L, Guo M, Zhang S, Wu J, Wang M, Shen Y, Peng X, Wang Z, Jiang W, Huang W. Zhuo L, et al. Among authors: wu j. Eur J Med Chem. 2024 Feb 5;265:116090. doi: 10.1016/j.ejmech.2023.116090. Epub 2023 Dec 30. Eur J Med Chem. 2024. PMID: 38169272

3

Identification of a novel 10-hydroxyevodiamine prodrug as a potent topoisomerase inhibitor with improved aqueous solubility for treatment of hepatocellular carcinoma.

Wei X, Zhang X, Peng Y, Wu J, Mo H, An Z, Deng X, Peng Y, Liu L, Jiang W, Chen J, Hu Z, Wang Z, Zhuo L. Wei X, et al. Among authors: wu j. Eur J Med Chem. 2024 Dec 5;279:116807. doi: 10.1016/j.ejmech.2024.116807. Epub 2024 Sep 1. Eur J Med Chem. 2024. PMID: 39243453

4

Discovery of 7-(1-methyl-1H-pyrazol-4-yl)-1,6-naphthyridine derivatives as potent inhibitors of rearranged during transfection (RET) and RET solvent-front mutants for overcoming selpercatinib resistance.

Wu J, Mo H, An Z, Tang Z, Deng X, Zhou H, Gong Y, Zheng C, Zhuo L, Tan S. Wu J, et al. Eur J Med Chem. 2024 Dec 5;279:116891. doi: 10.1016/j.ejmech.2024.116891. Epub 2024 Sep 19. Eur J Med Chem. 2024. PMID: 39316846

5

Novel N-phenyl-2-(aniline) benzamide hydrochloride salt development for colon cancer therapy.

Peng Y, Peng Y, Zhang W, Zhang S, Peng H, Li Z, Li B, Liu L, Zhuo L, Wang Z, Wu J, Jiang W. Peng Y, et al. Among authors: wu j. Front Pharmacol. 2024 Oct 30;15:1452904. doi: 10.3389/fphar.2024.1452904. eCollection 2024. Front Pharmacol. 2024. PMID: 39559733 Free PMC article.

6

From tryptamine to the discovery of efficient multi-target directed ligands against cholinesterase-associated neurodegenerative disorders.

Wu J, Zhang H, Wang Y, Yin G, Li Q, Zhuo L, Chen H, Wang Z. Wu J, et al. Front Pharmacol. 2022 Nov 28;13:1036030. doi: 10.3389/fphar.2022.1036030. eCollection 2022. Front Pharmacol. 2022. PMID: 36518670 Free PMC article.

7

Limonin inhibits the stemness of cancer stem-like cells derived from colorectal carcinoma cells potentially via blocking STAT3 signaling.

Zhang WF, Ruan CW, Wu JB, Wu GL, Wang XG, Chen HJ. Zhang WF, et al. World J Clin Oncol. 2024 Feb 24;15(2):317-328. doi: 10.5306/wjco.v15.i2.317. World J Clin Oncol. 2024. PMID: 38455137 Free PMC article.

8

Machine learning-based B cell-related diagnostic biomarker signature and molecular subtypes characteristic of ulcerative colitis.

Wu GL, Li L, Chen XY, Zhang WF, Wu JB, Yu X, Chen HJ. Wu GL, et al. Aging (Albany NY). 2024 Feb 5;16(3):2774-2788. doi: 10.18632/aging.205510. Epub 2024 Feb 5. Aging (Albany NY). 2024. PMID: 38319729 Free PMC article.

9

Ribosome profiling and single-cell RNA sequencing identify the unfolded protein response as a key regulator of pigeon lactation.

Liu J, Liu SF, Mao HR, Jiang HX, Liu SB, Xu XF, Wu JT, Liu X, Zhang WT, Hu XL, Chen B. Liu J, et al. Among authors: wu jt. Zool Res. 2025 Jan 18;46(1):54-74. doi: 10.24272/j.issn.2095-8137.2024.336. Zool Res. 2025. PMID: 39846187

10

HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding.

Zhu R, Wu J, Chen R, Zhou M, Cao S, Wu Z, Wang L, Zhang L, Zhu S. Zhu R, et al. Among authors: wu j. Front Vet Sci. 2025 Jan 8;11:1526600. doi: 10.3389/fvets.2024.1526600. eCollection 2024. Front Vet Sci. 2025. PMID: 39846021 Free PMC article.

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