Hu J - Search Results

1

HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.

Turnham RE, Pitea A, Jang GM, Xu Z, Lim HC, Choi AL, Von Dollen J, Levin RS, Webber JT, McCarthy E, Hu J, Li X, Che L, Singh A, Yoon A, Chan G, Kelley RK, Swaney DL, Zhang W, Bandyopadhyay S, Theis FJ, Eckhardt M, Chen X, Shokat KM, Ideker T, Krogan NJ, Gordan JD. Turnham RE, et al. Among authors: hu j. Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-0456. Online ahead of print. Cancer Res. 2024. PMID: 39652575

2

Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities.

Méndez-Lucas A, Li X, Hu J, Che L, Song X, Jia J, Wang J, Xie C, Driscoll PC, Tschaharganeh DF, Calvisi DF, Yuneva M, Chen X. Méndez-Lucas A, et al. Among authors: hu j. Cancer Res. 2017 Aug 15;77(16):4355-4364. doi: 10.1158/0008-5472.CAN-17-0498. Epub 2017 Jun 19. Cancer Res. 2017. PMID: 28630053 Free PMC article.

3

Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway.

Xu Z, Hu J, Cao H, Pilo MG, Cigliano A, Shao Z, Xu M, Ribback S, Dombrowski F, Calvisi DF, Chen X. Xu Z, et al. Among authors: hu j. Exp Mol Med. 2018 Jan 5;50(1):e417. doi: 10.1038/emm.2017.158. Exp Mol Med. 2018. PMID: 29303510 Free PMC article.

4

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.

Hu J, Che L, Li L, Pilo MG, Cigliano A, Ribback S, Li X, Latte G, Mela M, Evert M, Dombrowski F, Zheng G, Chen X, Calvisi DF. Hu J, et al. Sci Rep. 2016 Feb 9;6:20484. doi: 10.1038/srep20484. Sci Rep. 2016. PMID: 26857837 Free PMC article.

5

Correlation of exon 3 β-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma.

Hale G, Liu X, Hu J, Xu Z, Che L, Solomon D, Tsokos C, Shafizadeh N, Chen X, Gill R, Kakar S. Hale G, et al. Among authors: hu j. Mod Pathol. 2016 Nov;29(11):1370-1380. doi: 10.1038/modpathol.2016.122. Epub 2016 Jul 29. Mod Pathol. 2016. PMID: 27469330 Free PMC article.

6

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.

Zhang S, Song X, Cao D, Xu Z, Fan B, Che L, Hu J, Chen B, Dong M, Pilo MG, Cigliano A, Evert K, Ribback S, Dombrowski F, Pascale RM, Cossu A, Vidili G, Porcu A, Simile MM, Pes GM, Giannelli G, Gordan J, Wei L, Evert M, Cong W, Calvisi DF, Chen X. Zhang S, et al. Among authors: hu j. J Hepatol. 2017 Dec;67(6):1194-1203. doi: 10.1016/j.jhep.2017.07.006. Epub 2017 Jul 19. J Hepatol. 2017. PMID: 28733220 Free PMC article.

7

Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma.

Liu X, Hu J, Song X, Utpatel K, Zhang Y, Wang P, Lu X, Zhang J, Xu M, Su T, Che L, Wang J, Evert M, Calvisi DF, Chen X. Liu X, et al. Among authors: hu j. Cancers (Basel). 2019 Jul 3;11(7):930. doi: 10.3390/cancers11070930. Cancers (Basel). 2019. PMID: 31277283 Free PMC article.

8

Monocytes promote liver carcinogenesis in an oncogene-specific manner.

Juric V, Ruffell B, Evason KJ, Hu J, Che L, Wang L, Chen X, Bishop JM. Juric V, et al. Among authors: hu j. J Hepatol. 2016 Apr;64(4):881-90. doi: 10.1016/j.jhep.2015.11.025. Epub 2015 Nov 27. J Hepatol. 2016. PMID: 26639397 Free PMC article.

9

A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.

Liu P, Ge M, Hu J, Li X, Che L, Sun K, Cheng L, Huang Y, Pilo MG, Cigliano A, Pes GM, Pascale RM, Brozzetti S, Vidili G, Porcu A, Cossu A, Palmieri G, Sini MC, Ribback S, Dombrowski F, Tao J, Calvisi DF, Chen L, Chen X. Liu P, et al. Among authors: hu j. Hepatology. 2017 Jul;66(1):167-181. doi: 10.1002/hep.29183. Epub 2017 May 22. Hepatology. 2017. PMID: 28370287 Free PMC article.

10

Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.

Wang C, Che L, Hu J, Zhang S, Jiang L, Latte G, Demartis MI, Tao J, Gui B, Pilo MG, Ribback S, Dombrowski F, Evert M, Calvisi DF, Chen X. Wang C, et al. Among authors: hu j. Liver Int. 2016 Aug;36(8):1176-86. doi: 10.1111/liv.13055. Epub 2016 Jan 30. Liver Int. 2016. PMID: 26716908 Free PMC article.

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