Baker TK - Search Results

1

Imlunestrant is an Oral, Brain-Penetrant Selective Estrogen Receptor Degrader with Potent Antitumor Activity in ESR1 Wildtype and Mutant Breast Cancer.

Bhagwat SV, Mur C, Vandekopple M, Zhao B, Shen W, Marugán C, Capen A, Kindler L, Stephens JR, Huber L, Castanares MA, Garcia-Tapia D, Cohen JD, Bastian J, Mattioni B, Yuen E, Baker TK, Rodriguez Cruz V, Fei D, Manro JR, Pulliam N, Dowless MS, Ortiz Ruiz MJ, Yu C, Puca L, Klippel A, Bacchion F, Ismail-Khan R, Rodrik-Outmezguine V, Peng SB, Lallena MJ, Gong X, de Dios A. Bhagwat SV, et al. Among authors: baker tk. Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-2608. Online ahead of print. Cancer Res. 2024. PMID: 39652577

2

Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor.

McKinzie DL, Winneroski LL, Green SJ, Hembre EJ, Erickson JA, Willis BA, Monk SA, Aluise CD, Baker TK, Lopez JE, Hendle J, Beck JP, Brier RA, Boggs LN, Borders AR, Cocke PJ, Garcia-Losada P, Lowe SL, Mathes BM, May PC, Porter WJ, Stout SL, Timm DE, Watson BM, Yang Z, Mergott DJ. McKinzie DL, et al. Among authors: baker tk. J Med Chem. 2021 Jun 24;64(12):8076-8100. doi: 10.1021/acs.jmedchem.1c00489. Epub 2021 Jun 3. J Med Chem. 2021. PMID: 34081466

3

Temporal gene expression analysis of monolayer cultured rat hepatocytes.

Baker TK, Carfagna MA, Gao H, Dow ER, Li Q, Searfoss GH, Ryan TP. Baker TK, et al. Chem Res Toxicol. 2001 Sep;14(9):1218-31. doi: 10.1021/tx015518a. Chem Res Toxicol. 2001. PMID: 11559036

4

In Vitro L6 Irritation Assay Predicts Clinical Injection Site Reactions for Small Molecules.

Willy JA, Schulte NE, Kreklau EL, Walgren JL, Renninger ML, Baker TK. Willy JA, et al. Among authors: baker tk. Toxicol Sci. 2016 Jun;151(2):302-11. doi: 10.1093/toxsci/kfw050. Epub 2016 Mar 11. Toxicol Sci. 2016. PMID: 26969369

5

The Integrated Stress Response Regulates Cell Health of Cardiac Progenitors.

Searfoss GH, Paisley BM, Goldstein KM, Baker TK, Willy JA. Searfoss GH, et al. Among authors: baker tk. Toxicol Sci. 2019 Jan 1;167(1):202-210. doi: 10.1093/toxsci/kfy229. Toxicol Sci. 2019. PMID: 30215789

6

The Current Status and Use of Microphysiological Systems by the Pharmaceutical Industry: The International Consortium for Innovation and Quality Microphysiological Systems Affiliate Survey and Commentary.

Baker TK, Van Vleet TR, Mahalingaiah PK, Grandhi TSP, Evers R, Ekert J, Gosset JR, Chacko SA, Kopec AK. Baker TK, et al. Drug Metab Dispos. 2024 Feb 14;52(3):198-209. doi: 10.1124/dmd.123.001510. Drug Metab Dispos. 2024. PMID: 38123948

7

Advances in blood-brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure.

Brown JA, Faley SL, Shi Y, Hillgren KM, Sawada GA, Baker TK, Wikswo JP, Lippmann ES. Brown JA, et al. Among authors: baker tk. Fluids Barriers CNS. 2020 Jun 3;17(1):38. doi: 10.1186/s12987-020-00200-9. Fluids Barriers CNS. 2020. PMID: 32493346 Free PMC article.

8

What is your diagnosis? Serum biochemical data from Sprague-Dawley rats in a toxicology study.

Irizarry Rovira AR, Halstead BW, Jolly RA, Baker TK. Irizarry Rovira AR, et al. Among authors: baker tk. Vet Clin Pathol. 2011 Dec;40(4):559-560. doi: 10.1111/j.1939-165X.2011.00362.x. Epub 2011 Nov 3. Vet Clin Pathol. 2011. PMID: 22092965 No abstract available.

9

Toxicogenomics and cancer risk assessment: a framework for key event analysis and dose-response assessment for nongenotoxic carcinogens.

Bercu JP, Jolly RA, Flagella KM, Baker TK, Romero P, Stevens JL. Bercu JP, et al. Among authors: baker tk. Regul Toxicol Pharmacol. 2010 Dec;58(3):369-81. doi: 10.1016/j.yrtph.2010.08.002. Epub 2010 Aug 27. Regul Toxicol Pharmacol. 2010. PMID: 20801182

10

Gene expression analysis of the acute phase response using a canine microarray.

Higgins MA, Berridge BR, Mills BJ, Schultze AE, Gao H, Searfoss GH, Baker TK, Ryan TP. Higgins MA, et al. Among authors: baker tk. Toxicol Sci. 2003 Aug;74(2):470-84. doi: 10.1093/toxsci/kfg142. Epub 2003 May 28. Toxicol Sci. 2003. PMID: 12773757

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