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Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease.
Nunes JA, Santos-Júnior PFDS, Gomes MC, Ferreira LAS, Padilha EKA, Teixeira TR, Stanger EJ, Kaur Y, Silva EBD, Costa CACB, Freitas JD, Araújo-Júnior JX, Mendonça-Junior FJB, Giardini MA, Siqueira-Neto JL, Caffrey CR, Zhan P, Cardoso SH, Silva-Júnior EFD. Nunes JA, et al. Among authors: teixeira tr. Eur J Med Chem. 2025 Feb 5;283:117109. doi: 10.1016/j.ejmech.2024.117109. Epub 2024 Nov 28. Eur J Med Chem. 2025. PMID: 39653622
Clickable Probes for Pathogen Proteasomes: Synthesis and Applications.
Liu LJ, Lucero B, Manriquez-Rodriguez C, Francisco KR, Teixeira TR, Yohannan DJ, Ballatore C, Myers SA, O'Donoghue AJ, Caffrey CR. Liu LJ, et al. Among authors: teixeira tr. ACS Omega. 2024 Aug 2;9(32):34829-34840. doi: 10.1021/acsomega.4c04316. eCollection 2024 Aug 13. ACS Omega. 2024. PMID: 39157084 Free PMC article.
Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure-Activity Relationship and In Vivo Efficacy.
Liu LJ, Francisco KR, Sun YU, Serafim MSM, Amarasinghe DK, Teixeira TR, Lucero B, Kronenberger T, Elsayed W, Elwakeel H, Al-Hindy M, Almaliti J, Gerwick WH, O'Donoghue AJ, Caffrey CR. Liu LJ, et al. Among authors: teixeira tr. ACS Infect Dis. 2024 Dec 13;10(12):4182-4193. doi: 10.1021/acsinfecdis.4c00441. Epub 2024 Nov 26. ACS Infect Dis. 2024. PMID: 39589805 Free PMC article.
In vivo antischistosomal efficacy of Porcelia ponderosa γ-lactones.
Souza DCS, Totini CH, Cajás RA, Teixeira TR, Oliveira EA, Cirino ME, Souza MC, Salvadori MC, Teixeira FS, de Moraes J, Lago JHG. Souza DCS, et al. Among authors: teixeira tr. Phytomedicine. 2024 Dec;135:156045. doi: 10.1016/j.phymed.2024.156045. Epub 2024 Sep 12. Phytomedicine. 2024. PMID: 39299096
Pharmacophore Virtual Screening Identifies Riboflavin as an Inhibitor of the Schistosome Cathepsin B1 Protease with Antiparasitic Activity.
Cogo RM, Pavani TFA, Mengarda ACA, Cajas RA, Teixeira TR, Fukui-Silva L, Sun YU, Liu LJ, Amarasinghe DK, Yoon MC, Santos-Filho OA, de Moraes J, Caffrey CR, G G Rando D. Cogo RM, et al. Among authors: teixeira tr. ACS Omega. 2024 May 30;9(23):25356-25369. doi: 10.1021/acsomega.4c03376. eCollection 2024 Jun 11. ACS Omega. 2024. PMID: 38882094 Free PMC article.
32 results