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Page 1
Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome.
Matico R, Grauwen K, Chauhan D, Yu X, Abdiaj I, Adhikary S, Adriaensen I, Aranzazu GM, Alcázar J, Bassi M, Brisse E, Cañellas S, Chaudhuri S, Delgado F, Diéguez-Vázquez A, Du Jardin M, Eastham V, Finley M, Jacobs T, Keustermans K, Kuhn R, Llaveria J, Leenaerts J, Linares ML, Martín ML, Martín-Pérez R, Martínez C, Miller R, Muñoz FM, Muratore ME, Nooyens A, Perez-Benito L, Perrier M, Pietrak B, Serré J, Sharma S, Somers M, Suarez J, Tresadern G, Trabanco AA, Van den Bulck D, Van Gool M, Van Hauwermeiren F, Varghese T, Vega JA, Youssef SA, Edwards MJ, Oehlrich D, Van Opdenbosch N. Matico R, et al. Among authors: dieguez vazquez a. EMBO Mol Med. 2024 Dec 9. doi: 10.1038/s44321-024-00181-4. Online ahead of print. EMBO Mol Med. 2024. PMID: 39653810 Free article.
Late-Stage C(sp2)-C(sp3) Diversification via Nickel Oxidative Addition Complexes.
Odena C, Santiago TG, Linares ML, Castellanos-Blanco N, McGuire RT, Chaves-Arquero B, Alonso JM, Diéguez-Vázquez A, Tan E, Alcázar J, Buijnsters P, Cañellas S, Martin R. Odena C, et al. Among authors: dieguez vazquez a. J Am Chem Soc. 2024 Aug 7;146(31):21264-21270. doi: 10.1021/jacs.4c08404. Epub 2024 Jul 25. J Am Chem Soc. 2024. PMID: 39052124
PtCl4-catalyzed domino synthesis of fused bicyclic acetals.
Diéguez-Vázquez A, Tzschucke CC, Lam WY, Ley SV. Diéguez-Vázquez A, et al. Angew Chem Int Ed Engl. 2008;47(1):209-12. doi: 10.1002/anie.200704595. Angew Chem Int Ed Engl. 2008. PMID: 18061909 No abstract available.