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MoA Studies of the TEAD P-Site Binding Ligand MSC-4106 and Its Optimization to TEAD1-Selective Amide M3686.
Heinrich T, Schwarz D, Petersson C, Gunera J, Garg S, Schneider R, Keil M, Grimmeisen L, Unzue Lopez A, Albers L, Schlesiger S, Gambardella A, Bomke J, Carswell E, Schilke H, Diehl P, Doerfel B, Musil D, Trivier E, Broome R, Marshall S, Balsiger A, Friedrich E, Lemos AR, Santos SP, Sousa PMF, Freire F, Bandeiras TM, Bortoluzzi A, Wienke D. Heinrich T, et al. Among authors: santos sp. J Med Chem. 2024 Dec 20. doi: 10.1021/acs.jmedchem.4c01949. Online ahead of print. J Med Chem. 2024. PMID: 39704449
Diagnostic and prognostic implications of family history of fibrotic interstitial lung diseases.
Duminy-Luppi D, Alcaide-Aldeano A, Planas-Cerezales L, Bermudo G, Vicens-Zygmunt V, Luburich P, Del Río-Carrero B, Llatjós R, Pijuan L, Escobar I, Rivas F, Montes-Worboys A, Gutiérrez-Rodríguez Y, Rodríguez-Plaza D, Padró-Miquel A, Esteve-Garcia A, Fernández-Varas B, Flores C, Fuentes M, Dorca J, Santos S, Perona R, Günther A, Shull J, Molina-Molina M. Duminy-Luppi D, et al. Among authors: santos s. Respir Res. 2024 Dec 18;25(1):433. doi: 10.1186/s12931-024-03063-y. Respir Res. 2024. PMID: 39695595 Free PMC article.
Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography.
Greenwood HE, Barber AR, Edwards RS, Tyrrell WE, George ME, Dos Santos SN, Baark F, Tanc M, Khalil E, Falzone A, Ward NP, DeBlasi JM, Torrente L, Soni PN, Pearce DR, Firth G, Smith LM, Vilhelmsson Timmermand O, Huebner A, Swanton C, Hynds RE, DeNicola GM, Witney TH. Greenwood HE, et al. Among authors: dos santos sn. Nat Commun. 2024 Dec 17;15(1):10484. doi: 10.1038/s41467-024-54852-4. Nat Commun. 2024. PMID: 39690148 Free PMC article.
3,833 results