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Anticancer organorhodium and -iridium complexes with low toxicity in vivo but high potency in vitro: DNA damage, reactive oxygen species formation, and haemolytic activity.
Parveen S, Hanif M, Leung E, Tong KKH, Yang A, Astin J, De Zoysa GH, Steel TR, Goodman D, Movassaghi S, Söhnel T, Sarojini V, Jamieson SMF, Hartinger CG. Parveen S, et al. Chem Commun (Camb). 2019 Oct 3;55(80):12016-12019. doi: 10.1039/c9cc03822a. Chem Commun (Camb). 2019. PMID: 31498360
A Multitargeted Approach: Organorhodium Anticancer Agent Based on Vorinostat as a Potent Histone Deacetylase Inhibitor.
Hanif M, Arshad J, Astin JW, Rana Z, Zafar A, Movassaghi S, Leung E, Patel K, Söhnel T, Reynisson J, Sarojini V, Rosengren RJ, Jamieson SMF, Hartinger CG. Hanif M, et al. Among authors: astin jw. Angew Chem Int Ed Engl. 2020 Aug 17;59(34):14609-14614. doi: 10.1002/anie.202005758. Epub 2020 Jun 17. Angew Chem Int Ed Engl. 2020. PMID: 32431061
Plexin D1 negatively regulates zebrafish lymphatic development.
Britto DD, He J, Misa JP, Chen W, Kakadia PM, Grimm L, Herbert CD, Crosier KE, Crosier PS, Bohlander SK, Hogan BM, Hall CJ, Torres-Vázquez J, Astin JW. Britto DD, et al. Among authors: astin jw. Development. 2022 Nov 1;149(21):dev200560. doi: 10.1242/dev.200560. Epub 2022 Oct 24. Development. 2022. PMID: 36205097 Free PMC article.
41 results