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Discovery of 6α-Thiazolylcarboxamidonaltrexamine Derivative (NTZ) as a Potent and Central Nervous System Penetrant Opioid Receptor Modulator with Drug-like Properties for Potential Treatment of Opioid Use Disorder.
Huang B, Ma H, Pagare PP, Li M, Mendez RE, Gillespie JC, Poklis JL, Halquist MS, Stevens DL, Dewey WL, Selley DE, Zhang Y. Huang B, et al. Among authors: li m. ACS Pharmacol Transl Sci. 2024 Dec 5;7(12):4165-4182. doi: 10.1021/acsptsci.4c00593. eCollection 2024 Dec 13. ACS Pharmacol Transl Sci. 2024. PMID: 39698260
Resolving tissue complexity by multimodal spatial omics modeling with MISO.
Coleman K, Schroeder A, Loth M, Zhang D, Park JH, Sung JY, Blank N, Cowan AJ, Qian X, Chen J, Jiang J, Yan H, Samarah LZ, Clemenceau JR, Jang I, Kim M, Barnfather I, Rabinowitz JD, Deng Y, Lee EB, Lazar A, Gao J, Furth EE, Hwang TH, Wang L, Thaiss CA, Hu J, Li M. Coleman K, et al. Among authors: li m. Nat Methods. 2025 Jan 15. doi: 10.1038/s41592-024-02574-2. Online ahead of print. Nat Methods. 2025. PMID: 39815104
Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates.
Uckelmann M, Levina V, Taveneau C, Ng XH, Pandey V, Martinez J, Mendiratta S, Houx J, Boudes M, Venugopal H, Trépout S, Fulcher AJ, Zhang Q, Flanigan S, Li M, Sierecki E, Gambin Y, Das PP, Bell O, de Marco A, Davidovich C. Uckelmann M, et al. Among authors: li m. Nat Struct Mol Biol. 2025 Jan 15. doi: 10.1038/s41594-024-01457-6. Online ahead of print. Nat Struct Mol Biol. 2025. PMID: 39815045
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